Endodontic Microsurgery With the Use of L-PRF and an Occlusive Membrane: a Randomized Controlled Clinical Trial

• Register: ClinicalTrials.gov
• Last refreshed on: 12 December 2020
• Main ID: NCT02528240
• Date of registration: 14/08/2015
• Prospective Registration: No
• Primary sponsor: Universitaire Ziekenhuizen Leuven
• Public title: Endodontic Microsurgery With the Use of L-PRF and an Occlusive Membrane: a Randomized Controlled Clinical Trial
• Scientific title: Endodontic Microsurgery With the Use of L-PRF and an Occlusive Membrane: a Randomized Controlled Clinical Trial
• Date of first enrolment: August 2015
• Target sample size: 56
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02528240
• Study type: Interventional
• Study design: Allocation: Randomized. Intervention model: Factorial Assignment. Primary purpose: Treatment. Masking: Single (Outcomes Assessor).
• Phase: N/A

Countries of recruitment

Belgium

Key inclusion & exclusion criteria

Inclusion Criteria:

- Provision of Informed Consent

- Patients in need of an EMS

- EMS is the only option to cure the periapical lesion

Exclusion Criteria:

- Unlikely to be able to comply with the study procedures, as judged by the investigator

- Orthograde endodontic (re)treatment is indicated

- Known or suspected current malignancy

- History of chemotherapy within 5 years prior to study

- History of radiation in the head and neck region

- History of other metabolic bone diseases

- History of bleeding disorders

- HIV disease



Age minimum: 16 Years
Age maximum: N/A
Gender: All

Health Condition(s) or Problem(s) studied

Periapical Periodontitis

Intervention(s)

Procedure: EMS

Device: conebeam CT

Device: + occlusive membrane

Primary Outcome(s)

Patient related outcomes [Time Frame: 7 days]

Secondary Outcome(s)

Patient related outcomes [Time Frame: 7 days]

Secondary ID(s)

S58015 / B322201525314/ I / U

Source(s) of Monetary Support

Please refer to primary and secondary sponsors