Naproxen on Tooth Sensitivity Caused by In-office Bleaching

• Register: ClinicalTrials.gov
• Last refreshed on: 7 November 2016
• Main ID: NCT02463552
• Date of registration: 29/05/2015
• Prospective Registration: No
• Primary sponsor: Universidade Federal de Sergipe
• Public title: Naproxen on Tooth Sensitivity Caused by In-office Bleaching
• Scientific title: Rior Use of Naproxen on Tooth Sensitivity Reduction After In-office Bleaching: Randomized Clinical Trial
• Date of first enrolment: May 2015
• Target sample size: 50
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02463552
• Study type: Interventional
• Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Prevention
• Phase: N/A

Countries of recruitment

Brazil

Key inclusion & exclusion criteria

Inclusion Criteria:

- At least 18 years old patients of both genders presenting good general/oral health;

- All maxillary anterior teeth presenting shade equal or darker than 2M2 at Vita
bleachguide guide (Vita-Zahnfabrik, Germany);

- Signed the form accepting to participate of this study.

Exclusion Criteria:

- Presence of caries lesions, restorations and/or endodontic treatment at any maxillary
anterior teeth.

- Undergone tooth-whitening procedures;

- Pregnant/lactating;

- Presence of periodontal diseases;

- Presence of severe tooth discoloration by tetracycline stains or fluorosis;

- Any kind of medicine, bruxism habits or any other pathology that can cause
sensitivity (such as recession, dentin exposure);

- Continuous use of drugs with anti-inflammatory actions;

- Presence of tooth hypersensitivity at baseline measurement;

- Any known adverse effects caused by Naproxen;

- Non-attendance to any session of evaluation or bleaching.



Age minimum: 18 Years
Age maximum: 35 Years
Gender: Both

Health Condition(s) or Problem(s) studied

Toothache

Tooth Bleaching

Intervention(s)

Drug: Naproxen

Primary Outcome(s)

Risk to Tooth sensitivity - during procedure [Time Frame: During the bleaching procedure]

Secondary Outcome(s)

Level of tooth sensitivity - after procedure [Time Frame: 24 hours after bleaching prcedure]

Risk of tooth sensitivity - after procedure [Time Frame: 24 hours after bleaching prcedure]

Level of tooth sensitivity - during procedure [Time Frame: During the bleaching procedure]

Secondary ID(s)

UFSergipe

Source(s) of Monetary Support

Please refer to primary and secondary sponsors