Obstructive Sleep Apnoea in Ehlers-Danlos Syndrome

• Register: ClinicalTrials.gov
• Last refreshed on: 21 December 2015
• Main ID: NCT02435745
• Date of registration: 27/04/2015
• Prospective Registration: No
• Primary sponsor: University of Zurich
• Public title: Obstructive Sleep Apnoea in Ehlers-Danlos Syndrome OSA in EDS
• Scientific title: Obstructive Sleep Apnoea in Ehlers-Danlos Syndrome
• Date of first enrolment: April 2015
• Target sample size: 200
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02435745
• Study type: Observational
• Study design: Observational Model: Case Control, Time Perspective: Prospective
• Phase: N/A

Countries of recruitment

Switzerland

Contacts

• Name: Malcolm Kohler, Prof. MD
• Affiliation: University of Zurich

Key inclusion & exclusion criteria

Inclusion Criteria:

- Informed consent

- Diagnosis of Ehlers-Danlos Syndrome (not for control group)

Exclusion Criteria:

- Moribund or severe disease prohibiting protocol adherence

- Continuous positive airway pressure treatment for OSA during sleep study

- Physical or intellectual impairment precluding informed consent or protocol adherence

- Pregnant patients



Age minimum: N/A
Age maximum: N/A
Gender: Both

Health Condition(s) or Problem(s) studied

Ehlers-Danlos Syndrome

Obstructive Sleep Apnea

Primary Outcome(s)

Prevalence of OSA [Time Frame: up to 12 months]

Secondary Outcome(s)

Aortic diameter [Time Frame: up to 12 months]

Craniofacial phenotyping [Time Frame: up to 12 months]

Secondary ID(s)

KEK-ZH-Nr. 2015-0144

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

Ehlers-Danlos Net Switzerland

University Children's Hospital, Zurich