Effect of Remifentanil on the Recovery Profile After Prolonged Head and Neck Surgery

• Register: ClinicalTrials.gov
• Last refreshed on: 28 April 2015
• Main ID: NCT02416752
• Date of registration: 07/04/2015
• Prospective Registration: No
• Primary sponsor: Singapore General Hospital
• Public title: Effect of Remifentanil on the Recovery Profile After Prolonged Head and Neck Surgery
• Scientific title: Effect of Remifentanil on the Recovery Profile After Prolonged Head and Neck Surgery
• Date of first enrolment: August 2011
• Target sample size: 222
• Recruitment status: Completed
• URL: http://clinicaltrials.gov/show/NCT02416752
• Study type: Observational
• Study design: Observational Model: Case Control, Time Perspective: Prospective
• Phase: N/A

Countries of recruitment

Singapore

Key inclusion & exclusion criteria

Inclusion Criteria:

Patients with ASA I to II, scheduled for elective head and neck surgery with minimum
expected duration of 2 hours, requiring general anesthesia

Exclusion Criteria:

previous history of either drug or alcohol abuse those who have been using opioids for
long term mental disorder with difficult to understand pain scoring system ASA physical
status of III and above surgical procedure warranting elective postoperative ventilation



Age minimum: 21 Years
Age maximum: 80 Years
Gender: Both

Health Condition(s) or Problem(s) studied

Head and Neck Disorder

Pain

Intervention(s)

Drug: Remifentanil

Drug: choice of intra-operative opioids were left to the discretion of anesthesiologist

Primary Outcome(s)

Amount of opioids used in PACU in morphine equivalent [Time Frame: 90 minutes]

Secondary Outcome(s)

Adverse effects of remifentanil [Time Frame: 90 minutes]

Duration of PACU [Time Frame: 90 minutes]

Secondary ID(s)

Remi 2011/421/D SGH

Source(s) of Monetary Support

Please refer to primary and secondary sponsors