Myocardial Lipid and Creatine of Heart Failure on MRS

• Register: ClinicalTrials.gov
• Last refreshed on: 12 December 2020
• Main ID: NCT02378402
• Date of registration: 27/02/2015
• Prospective Registration: No
• Primary sponsor: Chang Gung Memorial Hospital
• Public title: Myocardial Lipid and Creatine of Heart Failure on MRS
• Scientific title: Exploring Myocardial Lipid and Creatine as Imaging Biomarkers for Patients of Heart Failure
• Date of first enrolment: January 2014
• Target sample size: 71
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02378402
• Study type: Observational

Countries of recruitment

Taiwan

Key inclusion & exclusion criteria

Inclusion Criteria:

1. heart failure patients diagnosed in the Keelung Chang Gung Memorial Hospital

2. without previous history of coronary artery disease

3. patients must be = 20 and = 80 years of age

4. patients must be willing to undergo standard treatment and follow up in the Heart
Failure Center

5. patients must be able to give informed consent.

Exclusion Criteria:

1. patients who are judged to be noncompliant to treatment or not accessible for follow
up

2. patients with contraindications to MR scanning, such as claustrophobia, cardiac
pacemaker, metal implants, or unable to cooperate for MRI study due to mental status

3. Severe renal function impairment (glomerular filtration rate less than 30
mL/min/1.73m2)

4. pregnant or breast-feeding status

5. history of open-heart surgery.



Age minimum: 20 Years
Age maximum: 80 Years
Gender: All

Health Condition(s) or Problem(s) studied

Myocardial Lipid

Intervention(s)

Other: Proton (1H-) magnetic resonance (MR) spectroscopy

Primary Outcome(s)

Myocaridal Lipid on MRS [Time Frame: 12 month]

Secondary ID(s)

102-2772A3

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Results

• Results available: Yes
• Date Posted: 21/10/2019
• URL: https://clinicaltrials.gov/ct2/show/results/NCT02378402