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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT02346695 |
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Date of registration:
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15/01/2015 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Association Between Left Ventricular Deformation and Aerobic Exercise Capacity in Untreated Arterial Hypertension
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Scientific title:
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Vascular and Biochemical Determinants of Left Ventricular Deformation and Twisting-untwisting and Their Interrelation With Aerobic Exercise Capacity in Untreated Arterial Hypertension |
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Date of first enrolment:
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June 2012 |
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Target sample size:
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480 |
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Recruitment status: |
Recruiting |
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URL:
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http://clinicaltrials.gov/show/NCT02346695 |
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Study type:
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Observational |
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Study design:
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Observational Model: Case Control, Time Perspective: Cross-Sectional
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Phase:
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N/A
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Countries of recruitment
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Greece
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Contacts
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Name:
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John Lekakis, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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2nd Cardiology Department, Attikon Hospital, University of Athens, Greece |
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Name:
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Ignatios Ikonomidis, MD |
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Address:
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Telephone:
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0030210583164 |
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Email:
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Affiliation:
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Name:
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Ignatios Ikonomidis, MD |
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Address:
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Telephone:
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00302105831264 |
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Email:
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Affiliation:
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Name:
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Ignatios Ikonomidis, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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2nd Cardiology Department, Attikon Hospital, University of Athens, Greece |
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Name:
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Helen Triantafyllidi, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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2nd Cardiology Department, Attikon Hospital, University of Athens, Greece |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- untreated patients with newly diagnosed essential hypertension
- normotensive subjects
Exclusion Criteria:
- history of diabetes
- familiar hyperlipidemia
- coronary CAD
- cardiomyopathy
- chronic pulmonary disease
Age minimum:
18 Years
Age maximum:
70 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Arterial Hypertension
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Primary Outcome(s)
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Left ventricular twisting-untwisting in hypertensive and normotensive subjects
[Time Frame: Baseline]
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Myocardial deformation in hypertensive and normotensive subjects
[Time Frame: Baseline]
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Vascular function in hypertensive and normotensive subjects
[Time Frame: Baseline]
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Secondary Outcome(s)
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Inflammation in hypertensive and normotensive subjects
[Time Frame: Baseline]
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Neurohumoral activation in hypertensive and normotensive subjects
[Time Frame: Baseline]
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Collagen synthesis in hypertensive and normotensive subjects
[Time Frame: Baseline]
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Exercise capacity in hypertensive subjects
[Time Frame: Baseline]
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Secondary ID(s)
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214/19-6-12
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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