Comparison Between Letrozole and Laparoscopic Ovarian Drilling in Women With Clomiphene Resistant Polycystic Ovarian Syndrome (PCOS)

• Register: ClinicalTrials.gov
• Last refreshed on: 8 August 2016
• Main ID: NCT02305693
• Date of registration: 26/11/2014
• Prospective Registration: No
• Primary sponsor: Cairo University
• Public title: Comparison Between Letrozole and Laparoscopic Ovarian Drilling in Women With Clomiphene Resistant Polycystic Ovarian Syndrome (PCOS)
• Scientific title: Comparison Between Letrozole and Laparoscopic Ovarian Drilling in Women With Clomiphene Resistant Polycystic Ovarian Syndrome (PCOS)
• Date of first enrolment: November 2014
• Target sample size: 140
• Recruitment status: Recruiting
• URL: https://clinicaltrials.gov/show/NCT02305693
• Study type: Interventional
• Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
• Phase: Phase 3

Countries of recruitment

Egypt

Contacts

• Name: AbdelGany MA Hassan, MRCOG, MD

Key inclusion & exclusion criteria

Inclusion Criteria:

- Clomiphene resistant PCOS women

Exclusion Criteria:

- Other causes of infertility.

- Hyperprolactinaemia.

- BMI>35.

- Previous Letrozole or LOD therapy.



Age minimum: 20 Years
Age maximum: 40 Years
Gender: Female

Health Condition(s) or Problem(s) studied

Infertility

Intervention(s)

Drug: Letrozole

Procedure: Laparoscopic ovarian drilling

Primary Outcome(s)

Ovulation [Time Frame: 6 weeks after starting the intervention]

Secondary Outcome(s)

Pregnancy [Time Frame: 6 months after starting the intervention]

Secondary ID(s)

Sub 7

Source(s) of Monetary Support

Please refer to primary and secondary sponsors