Autologous Serum Eye Drops With Contact Lenses for Corneal Epithelial Defects

• Register: ClinicalTrials.gov
• Last refreshed on: 28 September 2015
• Main ID: NCT02291731
• Date of registration: 07/11/2014
• Prospective Registration: No
• Primary sponsor: E-DA Hospital
• Public title: Autologous Serum Eye Drops With Contact Lenses for Corneal Epithelial Defects
• Scientific title: Topical Autologous Serum Eye Drops Combined With Silicone Hydrogen Lenses for theTreatment of Corneal Epithelial Defects
• Date of first enrolment: September 2014
• Target sample size: 21
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02291731
• Study type: Interventional
• Study design: Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
• Phase: N/A

Countries of recruitment

Taiwan

Contacts

• Name: Yan-Ming Chen, M.D.
• Affiliation: Department of Ophthalmology, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan

Key inclusion & exclusion criteria

Inclusion Criteria:

- Patients with PEDs for more than 1-month following conventional treatment, visiting
E-Da Hospital, Kaohsiung, Taiwan.

Exclusion Criteria:

- Patients had dry eye syndrome with a Schirmer test (<10 mm in 5 minutes) or lid
abnormalities.



Age minimum: N/A
Age maximum: N/A
Gender: Both

Health Condition(s) or Problem(s) studied

Corneal Diseases

Intervention(s)

Drug: Continuous use of topical autologous serum

Primary Outcome(s)

epithelial defect healing rate [Time Frame: 2-week]

Secondary Outcome(s)

epithelial defect recurrence rate [Time Frame: 3-month]

Secondary ID(s)

EMRP37103N

Source(s) of Monetary Support

Please refer to primary and secondary sponsors