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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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16 December 2017 |
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Main ID: |
NCT02271360 |
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Date of registration:
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19/10/2014 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Calcium Dobesilate Versus Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome
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Scientific title:
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Calcium Dobesilate Versus Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome |
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Date of first enrolment:
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April 2014 |
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Target sample size:
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200 |
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Recruitment status: |
Completed |
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URL:
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https://clinicaltrials.gov/show/NCT02271360 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Prevention. Masking: Single (Participant).
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Phase:
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Phase 2/Phase 3
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Countries of recruitment
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Egypt
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Contacts
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Name:
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ahmed saad, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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lecturer of ob/gyn |
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Name:
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khalid mohamed, MD |
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Address:
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Telephone:
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Email:
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Affiliation:
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lecturer of ob/gyn |
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Key inclusion & exclusion criteria
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Patients enrolled in the study were infertile women undergoing ICSI with one of the
following criteria: previous episodes of OHSS, polycystic ovaries (i.e., > 24 antral
follicles present on baseline ultrasound examination), high AMH (> 3.0 ng/mL), large number
of small follicles (8 to 12 mm) seen on ultrasound during ovarian stimulation, high s.E2 at
hCG trigger (E2 >3000 pg/ml or rapidly rising s.E2), presence of > 20 follicles by
ultrasound on day of retrieval or large number of oocytes retrieved (> 20).
Exclusion Criteria:
Age minimum:
22 Years
Age maximum:
44 Years
Gender:
Female
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Health Condition(s) or Problem(s) studied
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Infertility
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Intervention(s)
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Drug: Cabergoline
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Drug: Calcium Dobesilate
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Primary Outcome(s)
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Number of participants with ovarian hyperstimulation syndrome (OHSS)
[Time Frame: weekly for eight weeks]
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Secondary Outcome(s)
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pregnancy rate
[Time Frame: 14 days after embryos transfer]
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Secondary ID(s)
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khalid-ahmed 7
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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