Human Chorionic Gonadotrophin & Trigger

• Register: ClinicalTrials.gov
• Last refreshed on: 16 December 2017
• Main ID: NCT02264847
• Date of registration: 04/10/2014
• Prospective Registration: No
• Primary sponsor: Cairo University
• Public title: Human Chorionic Gonadotrophin & Trigger
• Scientific title: Trigger or Not to Trigger? : An Answer for an Old Question
• Date of first enrolment: October 2014
• Target sample size: 200
• Recruitment status: Recruiting
• URL: https://clinicaltrials.gov/show/NCT02264847
• Study type: Interventional
• Study design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: Single (Investigator).
• Phase: Phase 3

Countries of recruitment

Egypt

Contacts

• Name: Waleed M El-khayat, M.D.

• Name: Waleed EL-khayat, M.D.

• Name: Waleed El-khyatat, M.D.
• Affiliation: Cairo University

Key inclusion & exclusion criteria

Inclusion Criteria:

1. Normoprolactinemic and normogonadotropic (WHO class II ovarian dysfunction )

2. Primary infertility with oligomenorrhea (bleeding intervals between 35 days and 6
months) or amenorrhea (bleeding interval more than 6 months)

3. Age 18-40 years

4. Duration of primary infertility more than2 years

5. No history of ovulation induction treatment

6. No history of thyroid disease

7. Normal results on hysterosalpingogram

8. Husband with normal semen analysis

Exclusion Criteria:

1. Ovarian cyst

2. Endometrioma

3. Liver disease



Age minimum: 18 Years
Age maximum: 40 Years
Gender: Female

Health Condition(s) or Problem(s) studied

Ovulation Disorder

Intervention(s)

Drug: Human chorionic gonadotrophin

Drug: clomiphene citrate alone

Primary Outcome(s)

Ovulation rate [Time Frame: 1 year]

Secondary Outcome(s)

chemical pregnancy [Time Frame: 1 year]

Clinical pregnancy [Time Frame: 1 year]

Secondary ID(s)

5102014

A5102014

Source(s) of Monetary Support

Please refer to primary and secondary sponsors