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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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19 February 2015 |
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Main ID: |
NCT02261922 |
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Date of registration:
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07/10/2014 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Ticagrelor and Endothelial Function
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Scientific title:
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A Prospective Randomized Double Blind Study to Evaluate the Effect of Ticagrelor on Endothelial Function |
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Date of first enrolment:
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October 2014 |
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Target sample size:
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20 |
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Recruitment status: |
Recruiting |
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URL:
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http://clinicaltrials.gov/show/NCT02261922 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
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Phase:
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Phase 4
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Countries of recruitment
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Lebanon
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Contacts
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Name:
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Rabih Azar, MD, MPH |
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Address:
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Telephone:
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Email:
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razar@usj.edu.lb |
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Affiliation:
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Name:
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Rabih R Azar, MD, MPH |
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Address:
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Telephone:
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+9611615300 |
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Email:
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razar@usj.edu.lb |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- - Prior MI > 1 year old
- Prior PCI > 1 year old
- Prior CABG > 3 months old
- Known lesion causing more than 50% stenosis on coronary angiography
Exclusion Criteria:
- Acute coronary syndrome within the last 6 months
- Any history of bleeding
- Age > 75 years
- Weight < 65 kg
- Prior stroke or TIA
- Platelet count < 100,000
- Hemoglobin < 11 mg/dL
- Patients who have received ticagrelor, prasugrel or clopidogrel in the 3 months that
preceded randomization
- Patients who are taking anti-thrombotic therapy
Age minimum:
21 Years
Age maximum:
75 Years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Antiplatelet Agents; Endothelial Function; Pleotropic Effects
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Intervention(s)
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Drug: ticagrelor
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Drug: prasugrel
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Primary Outcome(s)
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flow mediated dilation of the brachial artery
[Time Frame: 8 +/- 2 days]
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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