Effect of Remote Ischemic Conditioning in Heart Attack Patients

• Register: ClinicalTrials.gov
• Last refreshed on: 16 December 2017
• Main ID: NCT02197117
• Date of registration: 18/07/2014
• Prospective Registration: No
• Primary sponsor: University College, London
• Public title: Effect of Remote Ischemic Conditioning in Heart Attack Patients ERIC-LYSIS
• Scientific title: Effect of Remote Ischaemic Conditioning in STEMI Patients Treated by thromboLYSIS: A Randomised Controlled Clinical Trial (the ERIC-LYSIS Study)
• Date of first enrolment: March 2011
• Target sample size: 519
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02197117
• Study type: Interventional
• Study design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: Single (Outcomes Assessor).
• Phase: N/A

Countries of recruitment

Mauritius

Key inclusion & exclusion criteria

Inclusion Criteria:

- Age >18 years

- Presentation within 12 hours of onset of chest pain

- ECG showing ST-segment elevation of =0.1mV in two contiguous leads (=0.2mV in leads
V1-V3)

Exclusion Criteria:

-None -



Age minimum: 18 Years
Age maximum: N/A
Gender: All

Health Condition(s) or Problem(s) studied

ST-segment Elevation Myocardial Infarction (STEMI)

Intervention(s)

Device: Remote ischemic conditioning

Device: Control

Primary Outcome(s)

Myocardial infarct size [Time Frame: Measured by 24 hr area under the curve serum CK-MB and Troponin-T sampled a time 0, 6, 12, and 24 hrs post-thrombolysis]

Secondary Outcome(s)

Acute kidney injury [Time Frame: Measured by serum creatinine at 24 hours]

Secondary ID(s)

ERIC-LYSIS

Source(s) of Monetary Support

Please refer to primary and secondary sponsors