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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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JPRN |
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Last refreshed on:
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17 October 2023 |
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Main ID: |
JPRN-UMIN000015685 |
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Date of registration:
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13/11/2014 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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Investigation of the impact of DPP-4 inhibition on serum brain natriuretic peptide level of diabetic patients with congestive heart failure.
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Scientific title:
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Investigation of the impact of DPP-4 inhibition on serum brain natriuretic peptide level of diabetic patients with congestive heart failure. - DPP-4 inhibitor and serum BNP level of diabetic patients with congestive heart failure. |
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Date of first enrolment:
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2014/11/13 |
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Target sample size:
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50 |
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Recruitment status: |
Recruiting |
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URL:
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https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000018232 |
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Study type:
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Interventional,observational |
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Study design:
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Single arm Non-randomized
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Phase:
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Not applicable
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Countries of recruitment
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Japan
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Contacts
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Name:
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Akihiro Isogawa |
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Address:
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1 Kanda Izumicho, Chiyoda-ku, Tokyo
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Telephone:
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+81-3-3862-9111 |
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Email:
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isogawa-tky@umin.ac.jp |
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Affiliation:
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Mitsui Memorial Hospital Division of diabetes |
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Name:
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Akihiro Isogawa |
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Address:
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1 Kanda Izumicho, Chiyoda-ku, Tokyo
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Telephone:
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+81-3-3862-9111 |
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Email:
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isogawa-tky@umin.ac.jp |
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Affiliation:
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Mitsui Memorial Hospital Division of diabetes |
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Key inclusion & exclusion criteria
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Inclusion criteria:
Exclusion criteria: 1. HbA1c over 9.0% 2. Patients changed treatment within 3 months before inclusion 3. Judged as ineligible by clinical investigators.
Age minimum:
20years-old
Age maximum:
Not applicable
Gender:
Male and Female
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Health Condition(s) or Problem(s) studied
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type 2 diabetes mellitus, congestive heart failure
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Intervention(s)
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sitagliptin, vildagliptin, alogliptin, linagliptin, teneligliptin, anaglitpin, saxagliptin
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Primary Outcome(s)
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Serum BNP level and cardiac function evaluated by echocardiography with and without DPP-4 inhibitor use.
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Secondary Outcome(s)
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Blood glucose, serum insulin, HbA1c, body weight, serum SDF-1 alpha, serum active GLP-1, serum active GIP with and without DPP-4 inhibitor use.
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Source(s) of Monetary Support
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Research fund of mitsukoshi health and welfare foundation
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Ethics review
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Status: YES
Approval date:
Contact:
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Results
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Results available:
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Yes |
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Date Posted:
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Date Completed:
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31/08/2015 |
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URL:
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