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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ISRCTN |
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Last refreshed on:
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6 July 2015 |
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Main ID: |
ISRCTN18890982 |
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Date of registration:
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20/10/2014 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Does ethnicity affect our body?s response to passive physical activity?
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Scientific title:
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Variability in the metabolic and cardiovascular effect of passive physical activity; influence of ethnicity |
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Date of first enrolment:
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01/08/2013 |
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Target sample size:
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90 |
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Recruitment status: |
Completed |
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URL:
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http://isrctn.com/ISRCTN18890982 |
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Study type:
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Interventional |
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Study design:
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Single centre randomized interventional study (Screening)
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Phase:
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Countries of recruitment
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Switzerland
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Contacts
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Name:
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Abdul
Dulloo |
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Address:
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Department of Medicine (Physiology)
University of Fribourg
Chemin du Musée 5
1700
Fribourg
Switzerland |
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Email:
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Affiliation:
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Name:
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. 20 ? 40 years old
2. Healthy as determined by medical history
3. European, Asian, African, or Indian ethnicity.
4. Signed consent given
Exclusion criteria: 1. Pregnancy
2. History of eating disorders
3. History of metabolic diseases (e.g. diabetes)
4. History of cardiovascular disease
5. History of neurological or psychiatric disorders
6. History of gastro-intestinal disorders
7. Any other condition that might impair the subject?s ability to participate in the study
Age minimum:
Age maximum:
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Passive physical activity
Nutritional, Metabolic, Endocrine
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Intervention(s)
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1. Whole Body Vibration. The participant will stand on a vibrating platform. Vibrations will be intermittent, with 10 vibration periods of 30 seconds separated by equal non-vibration periods. The participant will be instructed to hold a hand-rail and semi-flex the knees to prevent transmission of vibrations to the upper body (above the waist).
2. ?Passive Standing?. The participant will lie on a clinical tilting table, which will be slowly inclined in blocks of 20° (resting for 16 minutes at each level of incline) to a maximum of angle of 80 degrees to simulate the standing posture, but with little muscular effort being needed from the subject as their weight is supported by the tilting-table itself.
Each protocol will be conducted twice ? once when the participant is fasted and once after they have eaten a small standardized meal.
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Primary Outcome(s)
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Energy expenditure will be measured by indirect calorimetry before, during, and after each intervention
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Secondary Outcome(s)
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1. Cardiovascular response (heart rate and blood pressure) and EMG activity will be measured by continuous physiological monitoring before, during and after whole body vibration
2. Body composition will be measured at the start the study
3. Dietary and lifestyle information will be collected by questionnaire
4. Body temperature and habitual physical activity will be measured by wireless physiological monitoring over a period of one week
5. The interaction between each intervention and food will be measured (the protocol will be conducted once in the fasted state, and once after participants have ingested a small, standardized meal)
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Source(s) of Monetary Support
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Department of Medicine, University of Fribourg (Switzerland)
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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