Health risk assessment along the wastewater and faecal sludge chains in Kampala (Uganda) and Hanoi (Vietnam)

• Register: ISRCTN
• Last refreshed on: 20 February 2023
• Main ID: ISRCTN13601686
• Date of registration: 13/01/2015
• Prospective Registration: No
• Primary sponsor: Swiss Tropical and Public Health Institute
• Public title: Health risk assessment along the wastewater and faecal sludge chains in Kampala (Uganda) and Hanoi (Vietnam)
• Scientific title: Health risk assessment along the wastewater and faecal sludge chains: case study in Kampala and Hanoi
• Date of first enrolment: 08/10/2013
• Target sample size: 1000
• Recruitment status: Completed
• URL: https://www.isrctn.com/ISRCTN13601686
• Study type: Observational
• Study design: Cross-sectional survey, epidemiological survey, environmental sampling, quantiative microbial risk assessment (Other)
• Phase: Not Applicable

Countries of recruitment

Switzerland, Uganda, Viet Nam

Contacts

• Name: Guealdio Cisse

Key inclusion & exclusion criteria

Inclusion criteria:
1. Participants were enrolled in case they belong to following exposure groups: Wastewater treatment plant workers, faecal sludge workers, farmers and community members.
2. Willing to sign a written consent from, submit a stool sample and conduct a questionnaire interview

Exclusion criteria:
1. Too sick to attend school or participate in the study (e.g. severe diarrhoea, severe anaemia, high fever, etc.)
2. Absence of written informed consent
3. Person is younger than 18 years of age


Age minimum:
Age maximum:
Gender: Both

Health Condition(s) or Problem(s) studied

Communicable diseases (soil-transmitted helminth, Schistosoma mansoni and intestinal protozoa infection )
Infections and Infestations

Intervention(s)

Administer a questionnaire interview for about 30 minutes to obtain data on demographics, occupation, socio-economic status, hygienic behavior, consumption of water and food, disease symptoms, health seeking, risk perception and personal protective equipment. The data is entered directly into a data entry mask of a tablet computer during the interview and will be synchronized with a secure server from Swiss Tropical and Public Health Institute in Switzerland every evening. The access to the database is restricted to the main investigators of the study. After the analysis we will make the results anonymous and share them with the stakeholders and participants.

After the interview we will invite participants to provide a stool sample the next morning for the detection of parasitic infection. Stool samples will be analysed by a laboratory technician the Ministry of Public Health. The results will be announced as they become available and will remain confidential. In case we detect any parasitic infection we will come back to the participant and provide treatment for free. All participants tested positive for soil-transmitted helminth or Schistosoma mansoni will be treated with a single dose of albendazole (400 mg) and praziquantel (40 mg/kg), respectively.

Primary Outcome(s)

Differences in parasitic infection between exposure groups (worker, farmer, community members)

Secondary Outcome(s)

Prevalence of communicable diseases and related risk factor in an urban East-African and Southeast Asian setting

Secondary ID(s)

N/A

Source(s) of Monetary Support

Direktion für Entwicklung und Zusammenarbeit

Secondary Sponsor(s)

World Health Organization (WHO)

Ethics review

Status:
Approval date:
Contact:

1. Ethics committee of Basel (Ethikkommission beider Basel); 07/08/2013; ref: 137/13 2. Makerere University School of Public Health: Higher Degrees Research and Ethics Committee; 10/07/2014; ref: IRBOOO1l353 3. Uganda National Council of Science and Technology (UNCST) in Kampala, Uganda and office of the president of the republic of Uganda; approved study period: 08/10/2013-08/10/2015; ref: HS1487 4. Hanoi School of

Results

• Results available: Yes
• Date Completed: 08/10/2015