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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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IRCT |
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Last refreshed on:
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22 February 2018 |
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Main ID: |
IRCT2014121620341N1 |
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Date of registration:
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2014-12-31 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Does administration of clarithromycin prevent pneumonia due to ventilator use?
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Scientific title:
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The effect of clarithromycin in preventing ventilator associated pneumonia |
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Date of first enrolment:
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2013-05-04 |
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Target sample size:
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60 |
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Recruitment status: |
Complete |
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URL:
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http://en.irct.ir/trial/18042 |
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Study type:
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interventional |
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Study design:
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Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention.
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Phase:
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N/A
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Countries of recruitment
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Iran (Islamic Republic of)
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Contacts
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Name:
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Mohammad Reza Mirjalili
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Address:
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Shahid Sadoughi hospital, Riazi sq., Yazd, Iran
Yazd
Iran (Islamic Republic of) |
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Telephone:
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+98 35 3725 8771 |
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Email:
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dr.mirjalili@ssu.ac.ir |
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Affiliation:
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Shahid Sadoughi University of Medical Sciences |
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Name:
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Mohammad Reza Mirjalili
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Address:
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Shahid Sadoughi hospital, Riazi sq, Yazd, Iran
Yazd
Iran (Islamic Republic of) |
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Telephone:
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+98 35 3725 8771 |
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Email:
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dr.mirjalili@ssu.ac.ir |
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Affiliation:
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Shahid Sadoughi University of Medical Sciences |
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Key inclusion & exclusion criteria
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Inclusion criteria: Inclusion criteria: ICU admission
Exclusion criteria: Neutropenia (Absolute Neutrophil Count less than 500 cells/µl); HIV infection; second or three degree atrioventricular (AV) block; Receiving oral corticosteroids in the past month
Exclusion criteria:
Age minimum:
18 years
Age maximum:
80 years
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Pneumonia, unspecified
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ventilator-associated pneumonia.
Pneumonia, unspecified
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Intervention(s)
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Prevention
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Intervention: oral clarithromycin 500 mg/BD
Control: placebo.
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Intervention: oral clarithromycin 500 mg/BD
Control: placebo
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Primary Outcome(s)
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Pneumonia. Timepoint: 48 hours. Method of measurement: Tracheobronchial smear culture, Colony forming units more than 10000000.
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Secondary Outcome(s)
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?APACHI score. Timepoint: day 1, 5, and 10. Method of measurement: physical exam.
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Source(s) of Monetary Support
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Shahid Sadoughi University of Medical Sciences
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Ethics review
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Status: Approved
Approval date:
Contact:
ethics committee of Shahid sadoughi University of Medical Sciences
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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