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Note: This record shows only the 20 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: German Clinical Trials Register
Last refreshed on: 6 November 2017
Main ID:  DRKS00012779
Date of registration: 24/07/2017
Prospective Registration: No
Primary sponsor: Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH
Public title: Evoked Potentials after Painful Cutaneous Electrical Stimulation Depict Pain Relief during a Conditioned Pain Modulation
Scientific title: Evoked Potentials after Painful Cutaneous Electrical Stimulation Depict Pain Relief during a Conditioned Pain Modulation
Date of first enrolment: 01/07/2015
Target sample size: 20
Recruitment status: Complete: follow-up complete
URL:  http://www.drks.de/DRKS00012779
Study type:  interventional
Study design:  Allocation: Randomized controlled trial;. Masking: Blinded (patient/subject, assessor). Control: Active control (effective treament of control group). Assignment: Crossover. Study design purpose: Basic research/physiological study;  
Phase: 
Countries of recruitment
Germany
Contacts
Name: Oliver  Höffken
Address:  Bürkle-de-la-Camp Platz 1 44789 Bochum Germany
Telephone: 00492343020
Email: oliver.hoeffken@bergmannsheil.de
Affiliation:  Neurologische Klinik und PoliklinikBerufsgenossenschaftliches UniversitätsklinikumBergmannsheil GmbH
Name: Oliver  Höffken
Address:  Bürkle-de-la-Camp-Platz 1 44789 Bochum Germany
Telephone: 00492343020
Email: oliver.hoeffken@bergmannsheil.de
Affiliation:  Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH
Key inclusion & exclusion criteria
Inclusion criteria: Healthy subjects, age>18 years, given written informed consent
Exclusion criteria: Current pain, neuropathy, nerve lesions, topical drug treatment, history of neurological, psychiatric or severe cardiovascular diseases

Age minimum: 18 Years
Age maximum: 70 Years
Gender: Both, male and female
Health Condition(s) or Problem(s) studied
Healthy volunteers
Intervention(s)
Intervention 1: We examine the influcence of contralateral applied painful cold water (10°C) on PCES-EPs (Cortical evoked potentials) and PCES (=painful cutaneous electrical stimulation)-induced pain in healthy subjects. After 5 minutes we repeat testing using non-painful cold water (24°C). Intervention 2: We examine the influcence of contralateral applied non-painful cold water on PCES-EPs and PCES-induced pain in healthy subjects. After 5 minutes we repeat testing using painful cold water.
Primary Outcome(s)
Primary outcome of this trial is the reduction of PCES-EP induced by painful cold water. Therefore, we assessed the ratio of the amplitude of PCES-EP before and during conditioning cold water.
Secondary Outcome(s)
As secondary outcome parameter, we assessed the relief of PCES induced pain using a 101-point numerical rating scale before and during conditioning cold water as a ratio.
Secondary ID(s)
15-5300
Source(s) of Monetary Support
Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH
Secondary Sponsor(s)
Results
Results available:
Date Posted:
URL:
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