Brief inpatient treatment continued by videoconference based psychotherapy for patients with chronic major depression

• Register: German Clinical Trials Register
• Last refreshed on: 8 April 2024
• Main ID: DRKS00009874
• Date of registration: 29/01/2016
• Prospective Registration: No
• Primary sponsor: Klinik für Psychiatrie und Psychotherapie. Uniklinik Freiburg
• Public title: Brief inpatient treatment continued by videoconference based psychotherapy for patients with chronic major depression
• Scientific title: Brief inpatient treatment continued by videoconference based psychotherapy for patients with chronic major depression - CBASP-VCP
• Date of first enrolment: 06/10/2015
• Target sample size: 30
• Recruitment status: Recruiting stopped after recruiting started
• URL: http://drks.de/search/en/trial/DRKS00009874
• Study type: interventional
• Study design: Allocation: Non-randomized controlled study; Masking: Open (masking not used); Control: historical; Assignment: other; Study design purpose:
• Phase: N/A

Countries of recruitment

Germany

Contacts

• Name: Nicole Ower
• Affiliation: Universitätsklinikum FreiburgKlinik für Psychiatrie und Psychotherapie

• Name: Nicole Ower
• Affiliation: Universitätsklinikum FreiburgKlinik für Psychiatrie und Psychotherapie

Key inclusion & exclusion criteria

Inclusion criteria: - diagnosis of Chronic Depression
- Hamilton Rating Scale of Depression (HRSD-24) score>20
- in ongoing medical/psychiatric care
- age 18-70 years
- fluent in German language
- technical requirements (Internet access)
- informed consent
- treatment resistance (no response to two or more adequate trials of antidepressants and/or no response to at least two health-insurance-reimbursed psychotherapies with at least 22 sessions each).

Exclusion criteria: - history of bipolar disorder
- substance addiction (less than 3 months clean)
- antisocial or borderline personality disorder
- severe autism
- organic brain disorders
- severe physical illness
- acute risk of suicide or suicide attempt within the last 12 months

Age minimum: 18 Years
Age maximum: 70 Years
Gender: All

Health Condition(s) or Problem(s) studied

major chronic depression
F33

Recurrent depressive disorder

Intervention(s)

Group 1:
Intervetniongroup: 3 weeks inpatient CBASP treatment (2 single therapy sessions of 50 min per week) with following videoconference based outpatient CBASP treatment for 9 weeks (2 single therapy sessions of 50 min per week).

Group 2: Historical comparison group from existing data of patients who participated in a classical 12 weeks inpatient CBASP treatment (2 single therapy sessions of 50 min per week plus 2 h of CBASP-group therapy per week) .

Primary Outcome(s)

- Questionnaire on feasibility and acceptance. Completed by patients and therapists
- Hamilton Rating Scale for Depression (HAMD-24; Hamilton, 1960) T0, T1, T2, T3 (T0 : at admission to station , T1 : at discharge from station , T2 : at end of outpatient therapy , follow-up ( T3 ) : 3 months after completion of outpatient therapy (end of study)

Secondary Outcome(s)

- Structured Clinical Interview for DSM-IV Disorders (T0).
- Childhood Trauma Questionnaire (T0).
- Beck Depression Inventory (T0-T3).
- Clinical Global Impression Scale (T1-T2).
- Global Assessment of Functioning Scale (T1-T2).
- World Health Organization Quality of Life Instrument (T0-T3).
- Impact Message Inventory-R (therapist-patient-relationship) (T1-T2).

Source(s) of Monetary Support

Universitätsklinikum FreiburgKlinik für Psychiatrie und Psychotherapie

Ministerium für Wissenschaft, Fortschung und Kunst Baden-Württemberg

Ethics review

Status: Approved
Approval date: 18/08/2015
Contact:

[e-mail]

Ethik-Kommission der Albert-Ludwigs-Universität Freiburg

[phone]

[e-mail]

Results

• URL: http://drks.de/search/en/trial/DRKS00009874#studyResults