Acupuncture with different point selection methods in the treatment of migraine

• Register: ChiCTR
• Last refreshed on: 18 April 2017
• Main ID: ChiCTR-TRC-07000024
• Date of registration: 2007-11-21
• Prospective Registration: Yes
• Primary sponsor: Chengdu University of Traditional Chinese Medicine
• Public title: Acupuncture with different point selection methods in the treatment of migraine
• Scientific title: An assessment study of optimization design of acupuncture with different point selection methods in the treatment of migraine
• Date of first enrolment: 2008-01-01
• Target sample size: No acupuncture group:150;Bian Zheng group:150;Simulation group:150;Head puncture:150;
• Recruitment status: Completed
• URL: http://www.chictr.org.cn/showproj.aspx?proj=9501
• Study type: Interventional study
• Study design: Randomized parallel controlled trial
• Phase: New Treatment Measure Clinical Study

Countries of recruitment

China

Contacts

• Name: Yingkun Li

• Name: Yujia Cai
• Affiliation: Chengdu University of Traditional Chinese Medicine, West China Hospital, Sichuang University, Chengdu Hospital of Integrated TCM & WM

Key inclusion & exclusion criteria

Inclusion criteria: 1. male or female non-premonitory migraine patients between 18 and 65 years old, period of remission or onset;
2. apart from the diagnosis criteria according to ICHD-2, a diagnosis standard by traditional Chinese medicine theory must be fulfilled. ICHD-2 diagnosis criteria according to International Classification of Headache Disorders by HIS:(1) at least 5 headache attacks by history, and consistent with the (2) to (4) below:(2) last between 4 to 72 hours;
3. consistent with at least two of the following:
(1) unilateral location;
(2) pulsatility;
(3) moderate to severe degree;
(4) exacerbated by daily activities;
4. consistent with at least one of the following during one episode:
(1) nausea and/or vomiting;
(2) photophobia and/or phonophobia.
5. other secondary causes excluded. Diagnosis criteria by traditional Chinese medicine theory:
(1) Ganyang Shangkang Headache signsChief signs: headache, irritability, red eyes, bitter mouth.Secondary signs: flushing, dry mouth, red tongue, yellow Tai, Xuan pulse;
(2) Yuxue headache signs: Chief signs: fixed, persistent, pricking headache; Secondary signs: purple tongue, thin and light Tai, Chen or Xi pulse.
Exclusion criteria: 1. pregnancy or breast feeding period;
2. complicated with severe cerebral, liver, kidney, or hematopoietic system diseases, or Parkinson's disease, extra-pyramidal disorders, or mental defects, hypertension;
3. special migraine involvement, such as ophthalmoplegic migraine;
4. intake of migraine medication in the past month before inclusion, or abuse of such medication, i.e., intake of migraine medication for more than 10 days per month;
5. poor treatment compliance, such as fear of acupuncture; or difficult follow-up, such as living too afar without contact.

Age minimum: 15
Age maximum: 70
Gender: Both

Health Condition(s) or Problem(s) studied

Migraine

Intervention(s)

No acupuncture group:Anti-pain treatment by medicine;Bian Zheng group:Selection of puncture points will depends on the "Zheng". Electronic stimulating;Simulation group:Superficial puncture without "De Qi" and no electronic stimulating;Head puncture:Selection of acupuncture points and puncture methods based on WHO recommendation. Electronic stimulating;

Primary Outcome(s)

Frequency of headache;Rate of no improvement;

Secondary Outcome(s)

Catabatic rate or degree;Quality of life;Wastage of antipain drugs;Changes of TCM "Zheng";Cast-effictive analysis;

Source(s) of Monetary Support

Ministry of Science and Technology of China