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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ChiCTR |
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Last refreshed on:
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18 April 2017 |
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Main ID: |
ChiCTR-OOB-15005868 |
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Date of registration:
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2015-01-22 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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Repeat Collagen Cross-Linking for Keratoconus
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Scientific title:
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Repeat Collagen Cross-Linking for Keratoconus |
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Date of first enrolment:
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2015-02-04 |
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Target sample size:
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Case series:8; |
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Recruitment status: |
Pending |
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URL:
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http://www.chictr.org.cn/showproj.aspx?proj=10312 |
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Study type:
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Observational study |
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Study design:
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Case series
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Phase:
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Other
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Countries of recruitment
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China
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Contacts
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Name:
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Miss Wong Sin Ting Janice
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Address:
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Department of Ophthalmology & Visual Sciences The Chinese University of Hong Kong 3/F Hong Kong Eye Hospital 147K Argyle Street, Mongkok, Hong Kong SAR
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Telephone:
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+852 39435825 |
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Email:
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janicewong@cuhk.edu.hk |
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Affiliation:
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The Chinese University of Hong Kong |
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Name:
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Dr. Chow Wing See Vanissa
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Address:
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3/F, Hong Kong Eye Hospital, 147K, Argyle Street, Mongkok, Kowloon, Hong Kong
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Telephone:
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+852 39435825 |
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Email:
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vanissa.chow@gmail.com |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. Previously treated with accelerated CXL;
2. Progressive keratoconus after treatment, as defined by
(1) worsened best-corrected visual acuity not accountable by corneal scarring (or other lenticular or posterior segment diseases), and/or
(2) 1D increase in steepest curvature, >1D increase in manifest cylinder and >0.5D increase in manifest spherical equivalent observed at two consecutive occasions.
Exclusion criteria: 1. Central ECD less than at least 2000;
2. Corneal pachymetry <400um at thinnest point (on Pentacam);
3. Corneal scarring;
4. History of corneal surgery, herpetic eye disease, severe DES, LSCD, delayed epithelial healing;
5. Underlying autoimmune disease, pregnancy, nursing.
Age minimum:
13
Age maximum:
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Keratoconus
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Intervention(s)
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Case series:1. UV-A 3mW : 30 minutes; 2. 1% riboflavin: q2min x 15;
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Primary Outcome(s)
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Topography: Kmax, Kmean, anterior elevation, posterior elevation;
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Secondary Outcome(s)
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1. Visual acuity;2. Refraction;3. Endothelial cell density;4. Axial length;5. Pachymetry;6. Complications;
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Secondary ID(s)
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CUHK_CCT00444
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Source(s) of Monetary Support
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Hong Kong Eye Hospital
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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