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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ChiCTR |
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Last refreshed on:
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18 April 2017 |
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Main ID: |
ChiCTR-IPR-17011152 |
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Date of registration:
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2017-04-16 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Effect of dexmedetomidine on perioperative blood coagulation and fibrinolysis function
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Scientific title:
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Effect of dexmedetomidine on perioperative blood coagulation and fibrinolysis function |
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Date of first enrolment:
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2017-04-15 |
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Target sample size:
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Dex group:30;Con group:30; |
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Recruitment status: |
Recruiting |
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URL:
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http://www.chictr.org.cn/showproj.aspx?proj=18818 |
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Study type:
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Interventional study |
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Study design:
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Randomized parallel controlled trial
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Phase:
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Post-market
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Countries of recruitment
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China
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Contacts
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Name:
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Shao Dong-Hua
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Address:
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8 Dianli Road, Zhenjiang, Jiangsu, China
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Telephone:
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+86 18952819811 |
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Email:
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13805281211@163.com |
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Affiliation:
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Affiliated People's Hospital of Jiangsu University |
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Name:
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Zheng Chen
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Address:
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8 Dianli Road, Zhenjiang, Jiangsu, China
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Telephone:
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+86 18952819909 |
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Email:
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czczgljglj@163.com |
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Affiliation:
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Affiliated People's Hospital of Jiangsu University |
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Key inclusion & exclusion criteria
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Inclusion criteria: ASA I or II, aged =70 year.
Exclusion criteria: BMI=28 kg/m2, preoperative coagulation disorder, abnormal platelet count, hepatic and renal insufficiency, any kind of preoperative medication that interfere with coagulation, heart disorder and preoperative blood transfusion.
Age minimum:
40
Age maximum:
70
Gender:
Both
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Health Condition(s) or Problem(s) studied
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open radical gastrectomy
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Intervention(s)
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Dex group:Dexmedetomidine 0.5 ug/kg was intravenously infused over 10 minutes before anesthesia induction, followed by a rate of 0.5 ug/kg/h until peritoneal closure;Con group:Volume-matched normal saline;
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Primary Outcome(s)
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TEG;Standard coagulation function;The activity of plasma AT-III;The concentrations of protein C and s-TM;The concentrations of plasma PAP and t-PA and PAI;
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Secondary Outcome(s)
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Hematocrit and platelet count;The requirements of intraoperative propofol and remifentanil;
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Source(s) of Monetary Support
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Department of Anesthesiology, Affiliated People's Hospital of Jiangsu University
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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