Effects of Acupuncture and Moxibustion on Heart Rate Variability in Patients with Chronic Fatigue Syndrome

• Register: ChiCTR
• Last refreshed on: 18 April 2017
• Main ID: ChiCTR-IPR-15007383
• Date of registration: 2015-11-12
• Prospective Registration: No
• Primary sponsor: Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture & Moxibustion; Acupuncture & Moxibustion Institute, Hubei University of Chinese Medicine
• Public title: Effects of Acupuncture and Moxibustion on Heart Rate Variability in Patients with Chronic Fatigue Syndrome
• Scientific title: A Randomized Control Trial of Acupuncture and Moxibustion on Chronic Fatigue Syndrome and Heart Rate Variability
• Date of first enrolment: 2014-10-01
• Target sample size: acupuncture group:15;moxibustion:15;control group:15;
• Recruitment status: Completed
• URL: http://www.chictr.org.cn/showproj.aspx?proj=12452
• Study type: Interventional study
• Study design: Randomized parallel controlled trial
• Phase: Pilot study

Countries of recruitment

Austria

Contacts

• Name: Fengxia LIang

• Name: Qing Shu
• Affiliation: Hubei University of Chinese Medicine

Key inclusion & exclusion criteria

Inclusion criteria: 1. Patients with CFS who were 18 to 65 years old;
2. Patients who met the diagnostic criteria for CFS that were published by the Centers for Disease Control and Prevention in the United States;
3. Patients who had no skin injuries at the acupoints (ST36 (Zusanli), CV4 (Guanyuan)).
Exclusion criteria: 1. Participants who could not accept and were afraid of acupuncture in the acupuncture group;
2. Participants who suffered from heart and cerebrovascular diseases, serious lung disease, diabetes, neurological diseases, or severe primary diseases such as those of the liver, kidney, and the hematopoietic system;
3. Participants who suffered from a mental health disorder, Alzheimer's disease, or cancer;
4. Participants who had taken Chinese herbal medicine during the previous 4 weeks and preceding the investigation;
5. Pregnant women and nursing mothers;
6. Participants who suffered from thrombocytopenia and abnormalities of blood coagulation;
7. Participants with a history of alcohol or drug abuse.

Age minimum: 18
Age maximum: 65
Gender: Male

Health Condition(s) or Problem(s) studied

Chronic Fatigue Syndrome

Intervention(s)

acupuncture group:acupuncture at ST36, CV4;moxibustion:moxibustion at ST36, CV4;control group:acupuncture at ST36, CV4;

Primary Outcome(s)

Fatigue Assessment Instrument;

Secondary Outcome(s)

mean HR;SDNN;total HRV;LF;HF;lg LF/HF;

Source(s) of Monetary Support

Hubei Provincial Collaborative Innovation Center of Preventive Treatment by A;Eurasia Pacific Uninet (project EPU 04/2015); Austrian Federal Ministries of Research, Science and Economy and of Health.