Electrical Impedance Tomography-guided PEEP titration combined with low intraoperative tidal volume optimizes the lung protective ventilation strategy in patients undergoing laparoscopic surgery

• Register: ChiCTR
• Last refreshed on: 18 April 2017
• Main ID: ChiCTR-IPR-14005305
• Date of registration: 2014-10-08
• Prospective Registration: Yes
• Primary sponsor: Anesthesiology Department, Changzheng Hospital, Shanghai
• Public title: Electrical Impedance Tomography-guided PEEP titration combined with low intraoperative tidal volume optimizes the lung protective ventilation strategy in patients undergoing laparoscopic surgery
• Scientific title: Electrical Impedance Tomography-guided PEEP titration combined with low intraoperative tidal volume
• Date of first enrolment: 2014-10-14
• Target sample size: Control:50;Experimental:50;
• Recruitment status: Recruiting
• URL: http://www.chictr.org.cn/showproj.aspx?proj=9614
• Study type: Interventional study
• Study design: Randomized parallel controlled trial
• Phase: Other

Countries of recruitment

China

Contacts

• Name: Xingying He
• Affiliation: Anesthesiology Department, Changzheng Hospital, Sh

• Name: Xueyin Shi

Key inclusion & exclusion criteria

Inclusion criteria: Aged 18 years or older who were scheduled for laparoscopic abdominal surgery under general anaesthesia.
Exclusion criteria: (1) had severe cardiac or pulmonary comorbidities or another disorder that might have compromised safe trial procedure; (2) had a body-mass index higher than 40 kg.m-2; (3) presence of pregnancy, tracheostomy, facial, neck, or chest wall abnormalities; (4) abdominal aortic aneurysm surgery, chemotherapy, or immunosuppressive therapy within 3 months; (5) unwilling or unable to give informed consent.

Age minimum: 18
Age maximum: 80
Gender: Both

Health Condition(s) or Problem(s) studied

acute lung injury

Intervention(s)

Control:EIT;Experimental:received VT of 6mL/kg, and PEEP was adjusted;

Primary Outcome(s)

PEEP;

Source(s) of Monetary Support

research fund