|
Main
|
|
Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
|
Register:
|
ChiCTR |
|
Last refreshed on:
|
18 April 2017 |
|
Main ID: |
ChiCTR-IOR-14005318 |
|
Date of registration:
|
2009-12-20 |
|
Prospective Registration:
|
Yes |
|
Primary sponsor: |
|
|
Public title:
|
Myocardial effects of Intralipid postconditioning
|
|
Scientific title:
|
Myocardial effects of Intralipid postconditioning |
|
Date of first enrolment:
|
2014-10-01 |
|
Target sample size:
|
Control and ILPCgroup:60;Control vs ILPC-0min vs ILPC-10min:90; |
|
Recruitment status: |
Recruiting |
|
URL:
|
http://www.chictr.org.cn/showproj.aspx?proj=9636 |
|
Study type:
|
Interventional study |
|
Study design:
|
Randomized parallel controlled trial
|
|
Phase:
|
Other
|
|
|
Countries of recruitment
|
|
China
| | | | | | | |
|
Contacts
|
|
Name:
|
Ronghua Zhou
|
|
Address:
|
Departement of Anesthesiology,West China Hospital, No.37, Guo Xue Xiang, Chengdu, Sichuan, China
610041
|
|
Telephone:
|
+86 13880256449 |
|
Email:
|
wr.zhou@hotmail.com |
|
Affiliation:
|
|
|
|
Name:
|
Ronghua Zhou
|
|
Address:
|
Departement of Anesthesiology,West China Hospital, No.37, Guo Xue Xiang, Chengdu, Sichuan, China
610041
|
|
Telephone:
|
+86 13880256449 |
|
Email:
|
wr.zhou@hotmail.com |
|
Affiliation:
|
Departement of Anesthesiology,West China Hospital |
| |
|
Key inclusion & exclusion criteria
|
Inclusion criteria: The ethics committee of our institution approved the study. Written informed consent was obtained from all patients before inclusion. Consecutive patients scheduled for aortic valve surgery or mitral valve surgery, older than 18yr, were eligible for enrollment.
Exclusion criteria: Exclusion criteria were emergency surgery, combined coronary surgery, significant coronary stenosis(less than 70%), left ventricular (LV) ejection fraction less than 40%, renal insufficiency (serum creatinine level more than 150 umol/l),severe hepatic dysfunction, uncontrolled hypertension and hyperglycemia, current infections, any disorder associated with immunological dysfunction (e.g., malignancy, positive serologic test for the human immunodeficiency virus) in the last 6 months before presentation
Age minimum:
18
Age maximum:
65
Gender:
|
|
Health Condition(s) or Problem(s) studied
|
|
Cardiac Valve disease
|
|
Intervention(s)
|
|
Control and ILPCgroup:Step 1: Intralipid postconditioning ;Control vs ILPC-0min vs ILPC-10min:Step 2: Intralipid postconditioning was applied at;
|
|
Primary Outcome(s)
|
|
cTNI;CK-MB;BNP;h-FABP;
|
|
Secondary Outcome(s)
|
|
major adverse events occurring during;length of stay in hospital;length of stay in intensive care unit;extubation time;the use of the positive inotropic drugs;LVEF;hepatic function;renal function;
|
|
Source(s) of Monetary Support
|
|
Project supported by Science&Technology Agency of Sichuan Province, Approval Number: 2012FZ0123
|
|
Results
|
|
Results available:
|
|
|
Date Posted:
|
|
|
Date Completed:
|
|
|
URL:
|
|
|
|