|
Main
|
|
Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
|
Register:
|
ChiCTR |
|
Last refreshed on:
|
18 April 2017 |
|
Main ID: |
ChiCTR-DDD-15007425 |
|
Date of registration:
|
2015-11-19 |
|
Prospective Registration:
|
No |
|
Primary sponsor: |
|
|
Public title:
|
PET molecular imaging in the dopamine receptor study of adolescent patients with Tourette Syndrome
|
|
Scientific title:
|
PET molecular imaging in the dopamine receptor study of adolescent patients with Tourette Syndrome |
|
Date of first enrolment:
|
2015-11-01 |
|
Target sample size:
|
Target condition:0;Difficult condition:0 |
|
Recruitment status: |
Recruiting |
|
URL:
|
http://www.chictr.org.cn/showproj.aspx?proj=12529 |
|
Study type:
|
Diagnostic test |
|
Study design:
|
Diagnostic test: case-control
|
|
Phase:
|
Diagnostic New Technique Clincal Study
|
|
|
Countries of recruitment
|
|
China
| | | | | | | |
|
Contacts
|
|
Name:
|
Jianhua Feng
|
|
Address:
|
88 Jiefang Road, Hangzhou, Zhejiang, China
|
|
Telephone:
|
+86 17858610213 |
|
Email:
|
zyk112000@gmail.com |
|
Affiliation:
|
|
|
|
Name:
|
Haifeng Hou
|
|
Address:
|
88 Jiefang Road, Hangzhou, Zhejiang, China
|
|
Telephone:
|
+86 13767123896 |
|
Email:
|
houhf@pku.edu.cn |
|
Affiliation:
|
Second Affiliated Hospital of Zhejiang University School of Medicine |
| |
|
Key inclusion & exclusion criteria
|
Inclusion criteria: 1. Patients with TS: (1) age between 18 to 25 years; (2) History meet the criterion of American Diagnostic and Statistical Manual of Mental Disorders fourth Edition ( DSM-IV-TR ); (3) A total of 20 patients (Men and women each have 10 people);
2. Healthy volunteers (The data have been acquired in previous clinical study, which was proved by ethical review and recorded in Chinese Clinical Trial Registry. Registration number: ChiCTR-OCC-09000358): Men and women each have 5 people;
3. No history of physical, especially brain organic disease, and no history of substance use including analgesics, antiepileptics and antipsychotic. Patients of TS do not have other disease;
4. No other serious concomitant diseases;
5. Willing and able to follow the program during the study period;
6. Written informed consent.
Exclusion criteria: 1. History of allergies to Contrast agents or tracers;
2. Having received any experimental drugs or protocols in half a year before entering the group , that is, having participated in another experiment;
3. Current or past use of addictive drugs, analgesics, antiepileptics and antipsychotic;
4. Current or planned pregnancy;
5. Subjects receivied major surgery within 1 year before entering the group, or not yet fully recovered from the effects of major surgery;
6. Claustrophobic patients
7. Unwilling and unable to follow the program during the study period;
8. Current or past mood disorder, anxiety disorder, psychotic disorder, or mental retardation based on DSM-IV criteria.
Age minimum:
11
Age maximum:
18
Gender:
Both
|
|
Health Condition(s) or Problem(s) studied
|
|
Tourette syndrome
|
|
Intervention(s)
|
|
Gold Standard:;Index test:;
|
|
Primary Outcome(s)
|
|
Function of dopamine receptor;Function of 5-HT receptor;
|
|
Source(s) of Monetary Support
|
|
Supporting funds for key disciplines of Zhejiang Province
|
|
Results
|
|
Results available:
|
|
|
Date Posted:
|
|
|
Date Completed:
|
|
|
URL:
|
|
|
|