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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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CTRI |
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Last refreshed on:
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24 November 2021 |
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Main ID: |
CTRI/2017/05/008595 |
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Date of registration:
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19-05-2017 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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Study of platelet crossmatch in cancer patients
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Scientific title:
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Assessment of platelet crossmatch results by solid phase red cell adherence assay among adult hematooncology patients and its feasibility in a tertiary care oncology centre. |
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Date of first enrolment:
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25-05-2017 |
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Target sample size:
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50 |
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Recruitment status: |
Completed |
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URL:
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http://www.ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=18762 |
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Study type:
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Observational |
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Study design:
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Single Arm Trial
Method of generating randomization sequence:Not Applicable Method of allocation concealment:Not Applicable Blinding and masking:Not Applicable
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Phase:
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N/A
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Countries of recruitment
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India
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Contacts
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Name:
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Dr Pranita Bhikulal Sontakke
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Address:
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Department of Transfusion Medicine, service block , 5th floor,
Tata Memorial Hospital, Parel,
Mumbai- 400012 Ekta Nagar, Thoke lay-Out, Buldana-443001, Maharashtra
400012
Mumbai (Suburban), MAHARASHTRA
India |
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Telephone:
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022-24177000 |
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Email:
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pranitasontakke18@gmail.com |
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Affiliation:
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Tata Memorial Hospital, Mumbai |
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Name:
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Dr Priti D Desai
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Address:
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Department of Transfusion Medicine, service block , 5th floor,
Tata Memorial Hospital, Parel,
Mumbai- 400012 3- Periyar
Bhabha Atomic Research Campus, Aushaktinagar, Chembur,
Mumbai
400012
Mumbai (Suburban), MAHARASHTRA
India |
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Telephone:
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022-24177000 |
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Email:
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pranitasontakke18@gmail.com |
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Affiliation:
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Tata Memorial Hospital, Mumbai |
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Key inclusion & exclusion criteria
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Inclusion criteria: Adult patients of any hematological malignancies with history of packed red cell or platelet transfusion support on more than or equal to 2 occasions.
Exclusion criteria: 1) Pediatric patients
2) Patients having fever, infections, sepsis, splenomegaly, Disseminated Intravascular Coagulation (DIC).
3) Patients receiving amphotericin B
Age minimum:
Age maximum:
Gender:
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Health Condition(s) or Problem(s) studied
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Health Condition 1: null- Adult patients of any hematological malignancies with history of packed red cell or platelet transfusion support on more than or equal to 2 occasions.
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Primary Outcome(s)
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1 platelet crossmatch result- positive or negative
2 corrected platelet count increment (CCI) and correlation between these twoTimepoint: corrected count increment between 10 minutes to 1 hour of transfusion
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Secondary Outcome(s)
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we are trying to find out the effect of compatibility on post transfusion platelet increment and effectiveness of transfusion. In such multiply transfused patients, if we choose crossmatched platelets obtained right from the beginning, we will be able to get a better post-transfusion CCI. This may reduce the number of ineffective platelet transfusions. Ultimately this can reduce the burden on platelet inventory.Timepoint: after the study is completed(6 months)
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Source(s) of Monetary Support
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Tata Memorial Hospital, Dr Ernest Borges marg, Parel, Mumbai-100012
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Ethics review
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Status: Approved
Approval date: 13/04/2017
Contact:
Institutional Ethics Committee-I, TMH, Mumbai, Parel
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Results
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Results available:
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Date Posted:
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Date Completed:
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30/10/2017 |
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URL:
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