Integrated Psychological therapy for Schizophrenia

• Register: CTRI
• Last refreshed on: 24 November 2021
• Main ID: CTRI/2014/12/005338
• Date of registration: 31-12-2014
• Prospective Registration: No
• Primary sponsor: NIMHANS
• Public title: Integrated Psychological therapy for Schizophrenia
• Scientific title: Effectiveness of the Integrated Psychological Therapy in improving social functioning in patients with Schizophrenia - IPT
• Date of first enrolment: 08-08-2011
• Target sample size: 30
• Recruitment status: Completed
• URL: http://www.ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=4476
• Study type: Interventional
• Study design: Single Arm Trial; Method of generating randomization sequence:Not Applicable Method of allocation concealment:Not Applicable Blinding and masking:Not Applicable
• Phase: N/A

Countries of recruitment

India

Contacts

• Name: Dr Paulomi M Sudhir
• Affiliation: National Institute of Mental Health and Neurosciences

• Name: Dr Paulomi M Sudhir
• Affiliation: National Institute of Mental Health and Neurosciences

Key inclusion & exclusion criteria

Inclusion criteria: 1. Primary diagnosis of schizophrenia, or schizoaffective disorder, or Schizophreniform disorder (DSM IV TR)

2. Aged between 18-50 years.

3. Currently receiving treatment on outpatient basis

4. Maintained on the same dosage of medication in the two months prior to recruitment into the study and not been hospitalized in the two months prior to entry into the study

5. Minimum education up to Class V

6. English or Hindi speaking

7. Availability of a caregiver with whom patient is in contact


Exclusion criteria: . Inpatients.

. Co-morbid neurological conditions, history of head injury.

.Co-morbid Axis I diagnosis of substance dependence syndrome, or current psychoactive substance abuse (except nicotine dependence), severe depression with psychotic symptoms.

.Mental retardation on clinical assessment.

.Patients who have undergone neuropsychological assessment in the six months prior to entry into the study.

Patients who have received cognitive remediation or structured psychological therapy or social skills training in the past one year.

Patients who have received electro-convulsive treatment (ECT) in the six months prior to being recruited for the present study.



Age minimum:
Age maximum:
Gender:

Health Condition(s) or Problem(s) studied

Health Condition 1: F200- Paranoid schizophrenia Health Condition 2: null- Schizophrenia and Schizoaffective disorders

Intervention(s)

Intervention1: Psychological intervention ( Integrated Psychological Therapy: psychological therapy for 16-20 sessions that included social skills training and cognitive tasks
Control Intervention1: Not applicable: not applicable
Control Intervention2: Not applicable: No control group was taken

Primary Outcome(s)

social cognition, neurocognition, social functioning,Timepoint: Baseline, Post treatment and 3 month follow up

Secondary Outcome(s)

Psychiatric symptoms ( such as hallucinations, delusions, amotivation)Timepoint: baseline, post treatemnt and at 3 month follow-up

Secondary ID(s)

NIL

Source(s) of Monetary Support

None

Ethics review

Status: Approved
Approval date: 31/03/2010
Contact:

NIMHANS Institute Ethics Committee