Respiratory variation in two blood flow parameters in anaesthetised and ventilated children

• Register: CTRI
• Last refreshed on: 24 November 2021
• Main ID: CTRI/2014/12/005336
• Date of registration: 30-12-2014
• Prospective Registration: No
• Primary sponsor: Manipal University
• Public title: Respiratory variation in two blood flow parameters in anaesthetised and ventilated children
• Scientific title: Respiratory variation in aortic flow peak velocity and inferior vena cava diameter as indicator of fluid responsiveness in mechanically ventilated children- A cross sectional study.
• Date of first enrolment: 13-12-2011
• Target sample size: 42
• Recruitment status: Completed
• URL: http://www.ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=7898
• Study type: Interventional
• Study design: Single Arm Trial; Method of generating randomization sequence:Not Applicable Method of allocation concealment:Not Applicable Blinding and masking:Not Applicable
• Phase: N/A

Countries of recruitment

India

Contacts

• Name: Dr Sagar M S
• Affiliation: Kasturba Medical College

• Name: Dr Shreepathi K Achar
• Affiliation: Kasturba Medical College

Key inclusion & exclusion criteria

Inclusion criteria: healthy children posted for elective surgical procedures under general anaesthesia were chosen.
Exclusion criteria: Children with congenital or acquired heart diseases and cardiac arrhythmias

Children suffering from pulmonary and renal diseases

Children presenting with mass in the abdomen/raised intra-abdominal pressure



Age minimum:
Age maximum:
Gender:

Health Condition(s) or Problem(s) studied

Health Condition 1: null- Helathy children posted for planned surgery

Intervention(s)

Intervention1: Fluid Challenge: 10 ml/kg of crystalloid was administered
Intervention2: Fluid challenge: Study parameters are measured in patient before fluid challenge ,and the same measurements repeated again after the intervention i.e fluid challenge. The change in the parameters will be later calculated and compared with a standard method.
Control Intervention1: Two study parameters measured after fluid challenge: Study parameters are measured again after fluid challenge in the same group

Primary Outcome(s)

Respiratory variation in aortic flow peak velocity and inferior vena cava (IVC) diameter as predictors of fluid responsiveness

Timepoint: Intraoperative period

Secondary Outcome(s)

Effect of fluid challenge on fasting status

Timepoint: Intraoperative period

Secondary ID(s)

NIL

Source(s) of Monetary Support

Kasturba Hospital, Manipal

Ethics review

Status: Approved
Approval date: 13/12/2011
Contact:

Kasturba Medical College Institutional Ethics Committee