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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ANZCTR |
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Last refreshed on:
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11 June 2018 |
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Main ID: |
ACTRN12618000567224 |
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Date of registration:
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13/04/2018 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Comparison of efficacy of Micro needling with Platelet rich plasma versus Micro needling with Vitamin C for improvement in the appearance of Atrophic Facial Scars
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Scientific title:
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Comparison Of efficacy of Micro needling with Platelet rich plasma versus Micro needling with Vitamin C in Treatment of Atrophic Facial Scars |
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Date of first enrolment:
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1/11/2016 |
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Target sample size:
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60 |
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Recruitment status: |
Completed |
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URL:
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http://www.anzctr.org.au/ACTRN12618000567224.aspx |
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Study type:
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Interventional |
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Study design:
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Randomised controlled trial
Parallel |
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Phase:
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Not Applicable
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Key inclusion & exclusion criteria
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Health Condition(s) or Problem(s) studied
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post burn atrophic facial scars
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atrophic facial scars
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post acne atrophic facial scars
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post infectious e.g., chicken pox
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post trauma atrophic facial scars
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Intervention(s)
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topical local anesthetic (5% EMLA cream) is applied over scars 45 mins before procedure. Autologous PRP is prepared during this time interval ( of EMLA application) before starting microneedling, All the procedures will performed by primary researcher. Micro needling is done on each scarred skin in vertical, horizontal and both diagonal directions for 4 times (standard application) at a depth of 1.5mm, then PRP is injected at 0.1 ml/cm2 (approximate dose) in group A patients while vitamin C(500mg) 0.1 ml/cm2 is injected over the scarred areas in group B patients and micro needling is repeated again as above. PRP is made by taking 20ml of blood through venous puncture, first soft spin is at 1500 resolutions/min(RPM) for 10 minutes and then second hard spin is at 2500RPM for 10 minutes. from this 20ml we get 4.5ml of PRP Ice packs will be applied over treated areas in both groups and strict photo protective measures are advised during course of treatment for all the patients. Total of 3 sessions 4 weeks apart are done in all the cases.
time duration of each session is one hour and thirty minutes
primary researcher is post graduate resident in plastic surgery department of Jinnah burn and reconstructive surgery center.
PRP is injected at 0.1 ml/cm2 in group A patients while vitamin C 0.1 ml/cm2 is injected over the scarred areas in group B patients both before and after microneedling..
strength of vitamin C injection used is 500mg
a total of 4.5ml of prp is obtained from 20ml of blood.
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Source(s) of Monetary Support
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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