Pectoralis-serratus interfascial plane block vs. paravertebral block for acute post-mastectomy pain

• Register: ANZCTR
• Last refreshed on: 13 January 2020
• Main ID: ACTRN12615000669594
• Date of registration: 29/06/2015
• Prospective Registration: No
• Primary sponsor: diab fuad hetta
• Public title: Pectoralis-serratus interfascial plane block vs. paravertebral block for acute post-mastectomy pain
• Scientific title: In modified radical mastectomy, does Pectoralis-serratus interfascial plane block, compared to paravertebral block, reduce postoperative opioid consumption?
• Date of first enrolment: 25/11/2013
• Target sample size: 50
• Recruitment status: Completed
• URL: https://anzctr.org.au/ACTRN12615000669594.aspx
• Study type: Interventional
• Study design: Purpose: Treatment; Allocation: Randomised controlled trial;

Countries of recruitment

Egypt

Contacts

• Name: Dr diab fuad hetta

• Name: Dr diab fuad hetta

Key inclusion & exclusion criteria

Inclusion criteria: Adult women, American Society of Anesthesiologists (ASA) physical status class I–III, scheduled for unilateral modified radical mastectomy (MRM) with axillary evacuation
Exclusion criteria: The exclusion criteria included patients with a known allergy to bupivacaine or morphine, bleeding disorders, anatomical abnormalities, infection in the paravertebral region, pregnancy, breast feeding, severe obesity (body mass index >35 kg/m2), a history of drug or alcohol abuse and patients suffering from chronic pain or regularly receiving analgesics.

Age minimum: 18 Years
Age maximum: No limit
Gender: Females

Health Condition(s) or Problem(s) studied

Anaesthesiology - Anaesthetics

Post-operative pain following modified radical mastectomy;
Post-operative pain following modified radical mastectomy

Surgery - Other surgery

Intervention(s)

Before induction of anesthesia (pre-incision), for group PS, we will give pectoralis-serratus interfascial plane block, in which we will inject 10 ml of bupivacaine 0.25% between pectoralis major and minor muscles around the pectoral nerve. and another 20 ml of bupivacaine 0.25% between pectoralis minor and serratus anterior muscles at the level of rib 4 under ultrasonographic guidence

Primary Outcome(s)

postoperative 24 h morphine consumption recorded on patient chart[24 h post-operative]

Secondary Outcome(s)

The time to rescue analgesic recorded on patient chart [24 h post-operative]

Intensity of pain measured by VAS score recorded on patient chart[0 h (after recovery from anesthesia), 2 h, 4h, 8h, 16 h, 24 h post-operative]

Secondary ID(s)

none

Secondary Sponsor(s)

noha esmail ibrahim

Ethics review

Status: Approved
Approval date:
Contact:

SECI-IRB IORG0006563