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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ANZCTR |
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Last refreshed on:
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13 January 2020 |
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Main ID: |
ACTRN12615000613505 |
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Date of registration:
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12/06/2015 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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12 weeks of exercise training and its effect on immune function and glucose regulation.
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Scientific title:
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In overweight/obese males, does exercise intensity (high-intensity interval training vs continuous moderate-intensity) have an influence on immune function and glucose regulation? |
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Date of first enrolment:
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30/06/2015 |
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Target sample size:
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40 |
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Recruitment status: |
Not yet recruiting |
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URL:
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https://anzctr.org.au/ACTRN12615000613505.aspx |
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Study type:
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Interventional |
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Study design:
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Purpose: Treatment; Allocation: Randomised controlled trial; Masking: Open (masking not used);Assignment: Parallel;
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Phase:
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Not Applicable
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Countries of recruitment
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Australia
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Contacts
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Name:
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Mr Aaron Raman
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Address:
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REF3.001, Refectory building, Murdoch University, 90 South Street, Murdoch WA 6150
Australia |
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Telephone:
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+61893601389 |
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Email:
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A.Raman@Murdoch.edu.au |
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Affiliation:
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Name:
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Mr Aaron Raman
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Address:
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REF3.001, Refectory building, Murdoch University, 90 South Street, Murdoch WA 6150
Australia |
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Telephone:
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+61893601389 |
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Email:
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A.Raman@Murdoch.edu.au |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: BMI > 25
Sedentary
Exclusion criteria: Previously diagnosed with Type 2 diabetes
Have an inflammatory disease
Taking medication that may affect blood pressure, glucose control and/or cholesterol.
Age minimum:
18 Years
Age maximum:
44 Years
Gender:
Males
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Health Condition(s) or Problem(s) studied
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Metabolic and Endocrine - Diabetes
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Prevention of type 2 diabetes/prediabetes
;Overweight/obesity;
Prevention of type 2 diabetes/prediabetes
Overweight/obesity
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Inflammatory and Immune System - Normal development and function of the immune system
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Intervention(s)
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Exercise training consisting of either:
High intensity exercise (HIT) or continuous moderate-intensity (CME)
HIT - 6 bouts of high-intensity intermittent exercise @ 100% VO2max, on a stationary cycle ergometer with a work-to-rest ratio of 1:4 over a period of 30-minutes. Active recovery consists of cycling @ 50% VO2max and performance will be monitored on the software associated with the cycle ergometer.
CME - Moderate-intensity exercise @ 60% VO2max over a period of 30-minutes on a stationary cycle ergometer.
3 sessions per week
12 weeks
Group session
The researcher will administer the intervention. Dr. Timothy Fairchild is an ESSA Accredited Exercise Physiologist and Aaron Raman is a PhD student in exercise science.
Exercise adherence will be noted with an exercise log.
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Primary Outcome(s)
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Glucose control via an oral glucose tolerance test and continuous glucose monitor
Insulin sensitivity via serum insulin[Baseline, halfway (week 6) and post-training (week 12).]
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Secondary Outcome(s)
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Inflammatory markers; pro- and anti-inflammatory markers such as IL-6, CRP and IL-10.[Baseline, halfway (week 6) and post-training (week 12).
Blood samples will be collected in a fasted state.]
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Source(s) of Monetary Support
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McCusker Grant
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Ethics review
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Status: Approved
Approval date:
Contact:
Murdoch University Ethics Committee
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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