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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ANZCTR |
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Last refreshed on:
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13 January 2020 |
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Main ID: |
ACTRN12615000394549 |
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Date of registration:
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28/04/2015 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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Renal Replacement Therapy Intensity in Severe Acute Kidney Injury: An Individual Patient Data Meta-analysis of Randomized Trials
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Scientific title:
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Renal Replacement Therapy Intensity in Severe Acute Kidney Injury and its Effect on All-cause Mortality and Recovery to Dialysis Independence: An Individual Patient Data Meta-analysis of Randomized Trials |
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Date of first enrolment:
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09/04/2015 |
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Target sample size:
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3600 |
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Recruitment status: |
Recruiting |
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URL:
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https://anzctr.org.au/ACTRN12615000394549.aspx |
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Study type:
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Observational |
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Study design:
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Purpose: Screening;Duration: Cross-sectional;Selection: Defined population;Timing: Retrospective;
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Phase:
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Not Applicable
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Countries of recruitment
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Australia
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Germany
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Italy
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Netherlands
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Switzerland
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United States of America
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Contacts
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Name:
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Prof Rinaldo Bellomo
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Address:
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10-12 Ievers Terrace, Carlton VIC 3053,
Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
Australia |
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Telephone:
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61-3-9496 5992 |
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Email:
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rinaldo.bellomo@austin.org.au |
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Affiliation:
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Name:
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Prof Rinaldo Bellomo
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Address:
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10-12 Ievers Terrace, Carlton VIC 3053,
Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia
Australia |
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Telephone:
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61-3-9496 5992 |
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Email:
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rinaldo.bellomo@austin.org.au |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: All randomized controlled trials assessing the effects of different doses of renal replacement therapy (RRT) in patients with AKI.
Exclusion criteria: Patients with chronic kidney disease
Age minimum:
18 Years
Age maximum:
No limit
Gender:
Both males and females
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Health Condition(s) or Problem(s) studied
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Renal and Urogenital - Kidney disease
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Severe acute kidney injury requiring renal replacement therapy;
Severe acute kidney injury requiring renal replacement therapy
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Intervention(s)
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Higher intensity haemodialysis, a prescribed dose of 35 to 48 ml/kg/h or defined as published in the original publications
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Primary Outcome(s)
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All-cause mortality [At trial specific follow-up time points. ]
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Secondary Outcome(s)
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Renal replacement therapy (RRT) dependence, defined as the proportion of patients who were still RRT dependent at 7, 14, 28, 60 and 90 days, time to recovery to RRT independence [At trial specific follow-up time points]
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Secondary ID(s)
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Nil known
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Source(s) of Monetary Support
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Australian National Health and Medical Research Council (NHMRC) project grant
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Ethics review
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Status: Approved
Approval date:
Contact:
NSW Population and Health Services Research Ethics Committee
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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