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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ANZCTR |
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Last refreshed on:
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13 January 2020 |
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Main ID: |
ACTRN12614001042639 |
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Date of registration:
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26/09/2014 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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The effect of a short term, supervised exercise training intervention on longitudinal left ventricular function in patient with heart failure with preserved ejection fraction
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Scientific title:
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In patients with Heart Failure with Preserved Ejection Fraction (HFPEF), does short term supervised exercise training improve left ventricular longitudinal intrinsic function (global longitudinal strain)? |
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Date of first enrolment:
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07/10/2014 |
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Target sample size:
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25 |
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Recruitment status: |
Not yet recruiting |
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URL:
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https://anzctr.org.au/ACTRN12614001042639.aspx |
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Study type:
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Interventional |
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Study design:
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Purpose: Treatment; Allocation: Non-randomised trial; Masking: Open (masking not used);Assignment: Single group;Type of endpoint: Efficacy;
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Phase:
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Not Applicable
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Countries of recruitment
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Indonesia
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Contacts
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Name:
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Dr Sidhi Laksono Purwowiyoto
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Address:
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Perhimpunan Kardiologi Indonesia
RS Jantung dan Pembuluh Darah Harapan Kita
Jl Letjend S Parman Kav 87 Jakarta Barat 11410
Indonesia |
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Telephone:
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62218611816 |
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Email:
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sidhi.lp@gmail.com |
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Affiliation:
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Name:
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Dr Sidhi Laksono Purwowiyoto
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Address:
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Perhimpunan Kardiologi Indonesia (PERKI)
RS Jantung dan Pembuluh Darah Harapan Kita
Jl Letjend S Parman Kav87 Slipi Jakarta Barat 11410
Indonesia |
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Telephone:
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62215681111 |
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Email:
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sidhi.lp@gmail.com |
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion criteria: symptomatic HF NYHA class II-III, good LV EF (> 50%), diastolic dysfunction (more than grade I), NT pro BNP > 220pg/ml, BNP > 200 pg/ml, global normokinetic (no regional wall motion abnormality)
Exclusion criteria: valvular heart disease (more than moderate), pulmonary disease (COPD, moderate to severe asthma), acute coronary syndrome, stable angina pectoris, relevant musculoskeletal disease, symptomatic arrhytmias, BP > 150/100 mmHg
Age minimum:
55 Years
Age maximum:
65 Years
Gender:
Both males and females
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Health Condition(s) or Problem(s) studied
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Heart failure with preserved ejection fraction;
Heart failure with preserved ejection fraction
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Cardiovascular - Other cardiovascular diseases
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Intervention(s)
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One on one training with physiotherapist or sport trainer or registered nurse.
The exercise training will be 1 hour per day, 5 times a week for one month.
Intermittent and interval walking with upgrading to treadmill after two weeks exercise. Intermittent and interval waking protocol is 3 mins x fast paced walking at 70-80% max HR then followed by 2 mins slow recovery walking and repeated for 1 hour.
The exercise walking will be done in division of preventive rehabilitation facility building for 2 weeks duration and changed to treadmill for remaining 2 weeks.
The intensity of exercise is based on 70-80% maximal heart rate and 65% VO2max.
Each patient will be followed up on call and survey to their house.
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Primary Outcome(s)
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global longitudinal strain value (%) using 2D echocardiography speckle tracking imaging[at one month after supervised exercise training]
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Secondary Outcome(s)
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functional capacity using 6MWT[one month after intervention]
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quality of life using Minnesota Living with Heart Failure Questionnaire[baseline, 2 weeks and one month during intervention]
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Source(s) of Monetary Support
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Sidhi Laksono P
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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