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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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16 December 2017 |
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Main ID: |
NCT02203097 |
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Date of registration:
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25/07/2014 |
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Prospective Registration:
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No |
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Primary sponsor: |
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Public title:
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The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol Anesthesia
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Scientific title:
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The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol Anesthesia |
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Date of first enrolment:
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January 2014 |
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Target sample size:
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25 |
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Recruitment status: |
Completed |
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URL:
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https://clinicaltrials.gov/show/NCT02203097 |
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Study type:
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Interventional |
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Study design:
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Intervention model: Single Group Assignment. Primary purpose: Basic Science. Masking: None (Open Label).
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Phase:
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Phase 4
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Countries of recruitment
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Hungary
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Contacts
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Name:
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Csilla Molnár, MD, PhD |
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Address:
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Telephone:
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Email:
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Affiliation:
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University of Debrecen Medical and Health Science Center Department of Anesthesiology and Intensive Care 4032-Debrecen, Nagyerdei krt 98. Hungary Tel/fax: +36-52-255-347 |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Above the age 18
- American Society of Anesthesiologists (ASA) physical classification I. or II.
- Patients undergoing elective varicotomy, inguinal hernioplasty or breast surgery in
general anesthesia
Exclusion Criteria:
- Patients with cerebral, cardiac or systemic vascular disorders (hypertension,
diabetes)
- Patients receiving medication that affects the blood vessels (antihypertensive,
antidiabetic, antiarrhythmic medications)
Age minimum:
18 Years
Age maximum:
50 Years
Gender:
All
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Health Condition(s) or Problem(s) studied
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Propofol-anaesthesia Via Target-controlled Infusion
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Intervention(s)
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Drug: Propofol
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Procedure: Partial pressure of CO2 at the end of an exhaled breath
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Primary Outcome(s)
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Blood flow velocity in the middle cerebral artery
[Time Frame: Changes from baseline in blood flow velocity at the 15th, 20th and 25th minutes of the operation]
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Secondary Outcome(s)
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Changes in the central systolic and diastolic blood pressure
[Time Frame: Changes from baseline in central blood pressure at the 15th, 20th and 25th minutes of the operation]
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Arterial wall stiffness of the radial artery
[Time Frame: Changes from baseline in arterial stiffness at the 15th, 20th and 25th minutes of the operation]
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Secondary ID(s)
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030167-006/2014/OTIG
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2345
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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