Effect of Intermittent Versus Continuous Energy Restriction on Compensatory Mechanisms Activated During Weight Reduction

• Register: ClinicalTrials.gov
• Last refreshed on: 16 December 2017
• Main ID: NCT02169778
• Date of registration: 17/06/2014
• Prospective Registration: No
• Primary sponsor: Norwegian University of Science and Technology
• Public title: Effect of Intermittent Versus Continuous Energy Restriction on Compensatory Mechanisms Activated During Weight Reduction
• Scientific title: Effect of Intermittent Versus Continuous Energy Restriction on Compensatory Mechanisms Activated During Weight Reduction
• Date of first enrolment: August 2013
• Target sample size: 34
• Recruitment status: Completed
• URL: https://clinicaltrials.gov/show/NCT02169778
• Study type: Interventional
• Study design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: None (Open Label).
• Phase: N/A

Countries of recruitment

Norway

Contacts

• Name: Bård Kulseng, MD, PhD
• Affiliation: Norwegian University of Science and Technology

Key inclusion & exclusion criteria

Inclusion Criteria:

- adult (18-50 years old)

- obese healthy volunteers (30
- weight stable on the last three months (<2kg), not currently dieting to lose weight
and with an inactive lifestyle

Exclusion Criteria:

- history of endocrine/cardiovascular/pulmonary/kidney disease

- anaemia

- milk intolerance

- depression or other psychological disorders

- eating disorders

- drug or alcohol abuse within the last two years

- current medication known to affect appetite or induce weight loss

- a planned surgery during the study period

- participating in another research study



Age minimum: 18 Years
Age maximum: 50 Years
Gender: All

Health Condition(s) or Problem(s) studied

Obesity

Intervention(s)

Behavioral: Intermittent energy restricted diet

Behavioral: Continuous energy restricted diet

Primary Outcome(s)

Appetite related hormones [Time Frame: 12 weeks after the intervention]

Secondary Outcome(s)

Resting metabolic rate (RMR) [Time Frame: 12 weeks after the intervention]

Body composition [Time Frame: At 6 months from baseline]

Exercise efficiency [Time Frame: 12 weeks after the intervention]

Body composition [Time Frame: At 1 year from baseline]

Body composition [Time Frame: 12 weeks after the intervention]

Secondary ID(s)

2014/754

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

Monash University

Portuguese Research Council