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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.

Register:	ClinicalTrials.gov
Last refreshed on:	12 October 2015
Main ID:	NCT02127203
Date of registration:	25/04/2014
Prospective Registration:	Yes
Primary sponsor:	Damascus University
Public title:	Nitro-oxidative Stress in Periodontitis
Scientific title:	Assessment of Nitro - Oxidative Stress in Periodontal Disease
Date of first enrolment:	May 2014
Target sample size:	80
Recruitment status:	Completed
URL:	https://clinicaltrials.gov/show/NCT02127203
Study type:	Observational
Study design:	Observational Model: Case Control, Time Perspective: Cross-Sectional
Phase:	N/A

Countries of recruitment
Syrian Arab Republic

Contacts

Name:	Ali Abou Sulaiman, DDS MSc Phd
Address:
Telephone:
Email:
Affiliation:	Senior Lecturer in Periodontics, University of Damascus Dental School, Damascus

Name:	Abeer Alasadi, DDS
Address:
Telephone:
Email:
Affiliation:	MSc student, Department of Periodontology, University of Damascus Dental School

Name:	Francoise Qarabit, BSc MSc PhD
Address:
Telephone:
Email:
Affiliation:	Senior Lecturer in Chemistry, Department of Chemistry, Faculty of Sciences, University of Damascus, Baramkeh, Damascus, Syria

Key inclusion & exclusion criteria

Inclusion criteria:

- Patients of Syrian descent

- Systemically healthy

- Have at least 20 teeth

Exclusion criteria:

- Periodontal treatment during the last three months,

- History of major systemic diseases

- Consumption of anti oxidant supplements, antibiotics, anti inflammatory or any other
drugs in the last three months

- Smoking

- Alcohol consumption

- Pregnant and lactating women.

Age minimum: 18 Years
Age maximum: 60 Years
Gender: Both

Health Condition(s) or Problem(s) studied

Aggressive Periodontitis

Chronic Periodontitis

Intervention(s)

Primary Outcome(s)

Malondialdihyide levels in serum and gingival cervicular fluid [Time Frame: Within 24 hours after the collection of the serum and gingival fluid]

Nitric oxide levels in serum and gingival cervicular fluid [Time Frame: Within 24 hours after the collection of the serum and gingival fluid]

Secondary Outcome(s)

Clinical Attachment Loss (CAL) [Time Frame: One time assessment once sample recruitment has completed. This outcome will be assessed within one week before treatment provision]

Bleeding on Probing (BOP) [Time Frame: One time assessment once sample recruitment has completed. This outcome will be assessed within one week before treatment provision]

Plaque Index (PI) [Time Frame: One time assessment once sample recruitment has completed. This outcome will be assessed within one week before treatment provision]

Gingival Index (GI). [Time Frame: One time assessment once sample recruitment has completed. This outcome will be assessed within one week before treatment provision]

Periodontal Pocket Depth (PPD) [Time Frame: One time assessment once sample recruitment has completed. This outcome will be assessed within one week before treatment provision]

Secondary ID(s)

UDDS-Perio-03-2014

Source(s) of Monetary Support

Please refer to primary and secondary sponsors

Secondary Sponsor(s)

Ethics review

Results

Results available:
Date Posted:
Date Completed:
URL:

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