Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
Register:
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ClinicalTrials.gov |
Last refreshed on:
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19 February 2015 |
Main ID: |
NCT01111357 |
Date of registration:
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29/01/2010 |
Prospective Registration:
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Yes |
Primary sponsor: |
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Public title:
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Study of Human Leukocyte Antigen (HLA) Polymorphisms in Patients With Rheumatoid Arthritis
HLAPRPA |
Scientific title:
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Study of HLA Polymorphisms in French West-Indian Patients With Rheumatoid Arthritis : A Case Control Study |
Date of first enrolment:
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February 2010 |
Target sample size:
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200 |
Recruitment status: |
Completed |
URL:
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http://clinicaltrials.gov/show/NCT01111357 |
Study type:
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Observational |
Study design:
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Observational Model: Case Control, Time Perspective: Prospective
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Phase:
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N/A
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Countries of recruitment
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Martinique
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Contacts
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Name:
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Georges JEAN-BAPTISTE, Professor of medecine |
Address:
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Telephone:
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Email:
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Affiliation:
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CHU de Fort-de-France |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
- Diagnosis of Rheumatoid Arthritis according to ACR criteria
- Come from French West Indies (At least 3 grandparents are African-Caribbean)
- Sign written informed consent
Exclusion Criteria:
- Minor
- Patient with no Rheumatoid Arthritis according to ACR criteria
- Patient does not agree for a genetic study
For the control
Inclusion Criteria:
- Blood donor
- Sign written informed consent
- Patient with no Rheumatoid Arthritis according to ACR criteria
- Come from French West Indies (At least 3 grandparents are African-Caribbean)
Exclusion Criteria:
- Minor
- Patient does not agree for a genetic study
Age minimum:
18 Years
Age maximum:
N/A
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Rheumatoid Arthritis
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Intervention(s)
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Biological: Collect of 10 ml of peripheric blood for DNA extraction
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Primary Outcome(s)
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Difference of distribution of HLA alleles in patients and in healthy controls
[Time Frame: 1 day]
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Secondary Outcome(s)
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The association between the different HLA alleles among French West-Indian RA patients and the radiological damage.
[Time Frame: 1 day]
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The association between the different HLA alleles among French West-Indian RA patients and the autoantibodies production.
[Time Frame: 1 day]
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The association between the different HLA alleles among French West-Indian RA patients and the response to therapy
[Time Frame: 1 day]
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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