African trypanosomiasis

African trypanosomiasis, also known as sleeping sickness, is a severe disease, which is fatal if left untreated. It is closely related to a widespread infection of cattle known as N’gana, which restricts cattle rearing in many prime areas of Africa. Sleeping sickness claims comparatively few lives annually, but the risk of major epidemics means that surveillance and ongoing control measures must be maintained.

TDR has supported research on this disease for many years. Currently, our work is being conducted in the following areas:

Lead discovery for drugs for infectious tropical diseases

Innovative vector control interventions

Drug development and evaluation for helminths and other neglected tropical diseases

Accessible quality-assured diagnostics

Integrated community-based interventions