Pregnancy complications

Prelabour rupture of membranes

• Antibiotics for prelabour rupture of membranes at or near term
• Antibiotics for preterm rupture of membranes
• Planned early birth versus expectant management (waiting) for prelabour rupture of membranes at term (37 weeks or more)

Preterm birth

• Antenatal administration of corticosteroids for women at risk of preterm birth
• Antenatal lower genital tract infection screening and treatment programmes for preventing preterm delivery
• Bed rest in singleton pregnancies for preventing preterm birth
• Cervical stitch (cerclage) for preventing pregnancy loss in women
• Magnesium sulfate for women at risk of preterm birth for neuroprotection of the fetus
• Oral betamimetics for maintenance therapy after threatened preterm labour
• Prenatal administration of progesterone for preventing preterm birth in women considered at risk of preterm birth
• Prophylactic antibiotics for inhibiting preterm labour with intact membranes
• Tocolytics for preterm labour

Placenta previa

• Interventions for suspected placenta praevia

Prolonged pregnancy

• Induction of labour for improving birth outcomes for women at or beyond term

Infection during pregnancy

• Antibiotic regimens for management of intra-amniotic infection
• Antibiotics for asymptomatic bacteriuria in pregnancy
• Antibiotics for syphilis diagnosed during pregnancy
• Antibiotics for treating bacterial vaginosis in pregnancy
• Effect of administration of antihelminthics for soil-transmitted helminths during pregnancy
• Interventions to prevent malaria-related morbidity and mortality in pregnancy