New in RHL

Oral misoprostol for induction of labour

Oral misoprostol is as an effective agent for induction of labour. Compared with vaginal dinoprost or oxytocin, misoprostol use results in less frequent use of caesarean section.

Betamimetics for inhibiting preterm labour

Betamimetics delay preterm labour, but are associated with multiple adverse effects.

Tocolytics for preterm premature rupture of membranes

Current evidence does not support the administration of tocolysis for women with preterm premature rupture of membranes (PPROM).

Elective birth at 37 weeks’ gestation for women with an uncomplicated twin pregnancy

In twin pregnancies, compared with expectant management, elective births at 37 weeks’ gestation is not associated with increased risks of adverse outcomes.

Endometriosis: an overview of Cochrane Reviews

Gonadotrophin-releasing hormone (GnRH) analogues, levonorgestrel-releasing intrauterine system (LNG-IUD), danazol and laparoscopic treatment are effective in controlling pain in women with endometriosis. In women with subfertility associated with endometriosis undergoing assisted reproduction, three-month treatment with GnRH analogues increased pregnancy rate. Laparoscopic surgery was better than diagnostic laparoscopy alone in terms of pregnancy rate and live birth.

Fundal pressure during the second stage of labour

At the present time there is no evidence to either support or discourage the use of manual fundal pressure during the second stage of labour.

Fetal movement counting for assessment of fetal wellbeing

There is not enough evidence to either recommend or not recommend selective or routine fetal movement counting to improve outcomes in pregnancy.

Hospitalisation and bed rest for multiple pregnancy

Current evidence does not support hospitalization and bed rest for multiple pregnancy.

Laparoscopy for diagnosing resectability of disease in patients with advanced ovarian cancer

There is not enough evidence to conclude whether laparoscopy is better than clinical or radiological evaluations in predicting resectability of ovarian cancer.

Aromatase inhibitors for subfertile women with polycystic ovary syndrome

In women with polycystic ovary syndrome, treatment with letrozole (an aromatase inhibitor) appears to yield higher live birth and pregnancy rates than clomiphene citrate. However, letrozole did not appear to be better than laparoscopic ovarian drilling.

Enemas during labour

Giving an enema during labour does not appear to reduce puerperal or neonatal infection rates, episiotomy dehiscence or women’s satisfaction with the procedure.

Resources


Guidelines

Health-care practice guidance from WHO and other institutions

Methodological resources

Methodological and education resources for improved understanding of the concepts and discussions related to generation of best evidence

Videos
 

A set of training videos to help clinicians master details of manual or surgical procedures

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