New in RHL

Ambroxol for women at risk of preterm birth for preventing neonatal respiratory distress syndrome

There is insufficient evidence to support or refute the role of ambroxol in preventing neonatal respiratory distress syndrome in women at risk of pre-term birth. Further information is required regarding the benefits and risks of treatment.

Minimally invasive surgical techniques versus open myomectomy for uterine fibroids

Laparoscopic myomectomy is associated with lower pain scores and lower risk of postoperative fever than open myomectomy, with no significant difference in other post-operative adverse events.

High-dose versus low-dose oxytocin infusion regimens for induction of labour at term

There is no clear evidence to support either high-dose or low-dose oxytocin infusion regimens, and further trials are needed.

Cervical stitch (cerclage) for preventing preterm birth in multiple pregnancy

This review found no evidence of benefit from cervical cerclage for preventing preterm birth in multiple pregnancy, and in women with cervical changes cerclage was associated with increased risks to the newborn.

Drugs for preventing malaria in pregnant women in endemic areas

Malaria chemoprevention for pregnant women in endemic areas has clinically important benefits for mothers and newborns

Skin preparation for preventing infection following caesarean section

Strategies to minimize post-caesarean section sepsis may contribute to reduction of maternal mortality and morbidity. This review found no significant differences between various types and methods of antiseptics, except very low quality evidence of reduced skin bacteria colony counts with chlorhexidine gluconate versus povidone-iodine. More research is needed.

Digital vaginal examination for routine assessment and identification of delay in active labour

Digital vaginal examination at intervals of four hours is recommended for routine assessment and identification of delay in active labour.

Effect of partogram use on outcomes for women in spontaneous labour at term

Active phase partograph with a four-hour action line is recommended for monitoring the progress of labour.

Facilitators and barriers to giving birth in facilities in low- and middle-income countries

Strategies and incentives to promote and sustain respectful, non-abusive, high quality care during facility-based childbirth are required.

Magnesium sulphate for preventing preterm birth in threatened preterm labour

Magnesium sulphate is not effective for reducing the risk of preterm birth and its may use may increase the risk of mortality

Probiotics for preventing preterm labour

Although the use of probiotics is effective in treatment of vaginal infection, currently there is no evidence to support its use for preventing preterm labour.



Health-care practice guidance from WHO and other institutions

Methodological resources

Methodological and education resources for improved understanding of the concepts and discussions related to generation of best evidence


A set of training videos to help clinicians master details of manual or surgical procedures

RHL on iPad

Available for iPad, the RHL app allows you to access the entire library offline