There is insufficient evidence to support the routine use of antibiotics in the second and third trimesters to prevent infectious complications. However their use may reduce the risk of preterm delivery in selected patients, and may reduce the risk of postpartum infections.
Delaying the introduction of progressive enteral feeds for very low birth weight infants does not affect the risk of NEC or death. It delays the time until full enteral feeding is achieved; however, the clinical importance of this is not yet clear.
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