Administration of antibiotics to women with PROM is associated with short-term delay in delivery and reduction in maternal and neonatal morbidity. However, in the longer-term antibiotic use for PROM has little effect.
Administration of calcium channel blockers (CCB) to women in preterm labour is associated with a significant reduction in preterm birth and short-term reduction in neonatal morbidity. However, no differences in perinatal mortality and in long-term outcomes were seen. Available data do not allow firm conclusions to be drawn from this review.
There is significant reduction in stillbirth, perinatal and neonatal mortality in the trained versus untrained TBA clusters. However, no clear benefit could be demonstrated with additional or advanced TBA training though, overall neonatal death rate may be lower. The results may be encouraging but more evidence is needed to establish any concrete inference.
There is no clear evidence that specialized antenatal clinics improve maternal and infant outcomes. However, the included trials lacked sufficient statistical power to detect any possible difference between groups.
This review assessed the effectiveness and safety of different surgical approaches to hysterectomy for women with benign gynecological conditions. There is insufficient evidence to make a strong recommendation regarding the optimal surgical management of benign gynecological conditions.
Repeat doses of corticosteroids should be offered to women at risk of preterm birth who remain undelivered seven or more days after initial course of corticosteroids to reduce the risk of respiratory distress syndrome and serious neonatal health problems.
Reduced visits programmes of antenatal care are associated with an increase in perinatal mortality compared to standard care. Women are less satisfied with the reduced visits schedule and gaps between visits. Reduced visits schedule may be associated with lower costs.
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