These treatment guidelines are intended to give simple guidance for the training of primary health care workers using basic units. In the dosage guidelines, five age groups have been distinguished, except for the treatment of diarrhoea with oral rehydration fluid where six age and weight categories are used. When dosage is shown as 1 tab x 2, one tablet should be taken in the morning and one before bedtime. When dosage is shown as 2 tab x 3, two tablets should be taken in the morning, two should be taken in the middle of the day and two before bedtime.

Photo: CICR/G. Leblanc
The treatment guidelines contain the following diagnostic/symptom groups:
• anaemia
• pain
• diarrhoea (see detailed diagnosis and treatment schedules in Annex 2)
• fever
• respiratory tract infections (see detailed diagnosis and treatment schedules in Annex 3)
• ear infections
• measles
• eyes
• skin conditions
• sexually transmitted and urinary tract infections
• preventive care in pregnancy
• worms.
Anaemia
Weight |
0 - <4 kg |
4 - <8 kg |
8 - <15 kg |
15 - <35 kg |
35 kg + |
Age |
0 - <2 mths. |
2 mths. - <1 yr. |
1 - <5 yrs. |
5 - <15 yrs. |
15 yrs. + |
Diagnosis Symptom |
|
Severe anaemia (oedema, dizziness, shortness of breath) |
Refer |
Moderate anaemia (pallor and tiredness) |
Refer |
ferrous sulfate + folic acid 1 tab daily for at least 2 months |
ferrous sulfate + folic acid 2 tab daily for at least 2 months |
ferrous sulfate + folic acid 3 tab daily for at least 2 months |
ferrous sultate + folic acid 3 tab daily for at least 2 months |
Pain
Weight |
0 - <4 kg |
4 - <8 kg |
8 - <15 kg |
15 - <35 kg |
35 kg + |
Age |
0 - <2 mths. |
2 mths. - <1 yr. |
1 - <5 yrs. |
5 - <15 yrs. |
15 yrs. + |
Diagnosis Symptom |
|
|
Pain
headache, joint pain, toothache)
|
|
paracetamol tab 100 mg 1/2 tab x 3 |
paracetamol tab 100 mg 1 tab x 3 |
ASA32,33 tab 300 mg 1 tab x 3 |
ASA tab 300 mg 2 tab x 3 |
Stomach pain |
|
|
Refer |
aluminium hydroxide 1/2 tab x 3 for 3 days |
aluminium hydroxide 1 tab x 3 for 3 days |
32ASA = acetylsalicylic acid.
33For children under 12 paracetamol is to be preferred because of the risk of Reye’s Syndrome.
Diarrhoea
Weight |
0 - <5 kg |
5 - 7.9 kg |
8 - 10.9 kg |
11 - 15.9 kg |
16 - 29.9 kg |
30 kg + |
Age* |
Less than 4 months |
4 - 11 months |
12 - 23 months |
2 - 4 years |
5 - 14 years |
15 years or older |
Diagnosis Symptom |
|
Diarrhoea with some dehydration (Plan B, WHO) Annex 2c |
Approximate amount of ORS solution to give in the first 4 hours. |
Quantity of ORS in mls. |
200 - 400 |
400 - 600 |
600 - 800 |
800 - 1,200 |
1,200 - 2,200 |
2,200 - 4,000 |
Diarrhoea lasting more than two weeks or in malnourished or poor condition patient |
Give ORS according to dehydration stage and refer. |
Bloody diarrhoea34 (check the presence of blood in stools) |
Give ORS according to dehydration stage and refer. |
Diarrhoea with severe dehydration (Plan C, WHO) Annex 2d |
Refer patient for nasogastric tube and/or IV treatment. |
Diarrhoea with no dehydration (Plan A, WHO), Annex 2b |
Continue to feed. Advise the patient to return to the health worker in case of frequent stools, increased thirst, sunken eyes, fever or when the patient does not eat or drink normally, or does not get better within three days, or develops blood in the stool or repeated vomiting. |
*Use the patients age only when you do not know the weight. The approximate amount of ORS required (in ml) can also be calculated be multiplying the patient’s weight (in grams) times 0.075.
34Protocol to be established according to epidemiological data.
Use of drugs for children with diarrhoea
|
• ANTIBIOTICS should ONLY be used for dysentery and for suspected cholera cases with severe dehydration. Otherwise they are ineffective and should NOT be given.
• ANTIPARASITIC drugs should ONLY be used for:
- Amoebiasis, after antibiotic treatment of bloody diarrhoea for shigella has failed or trophozoites of E. Histolytica containing red blood cells are seen in the faeces.
- Giardiasis, when diarrhoea has lasted at least 14 days and cysts or trophozoites of Giardia are seen in faeces or small bowel fluid.
• ANTIDIARRHOEAL DRUGS and ANTIEMETICS should NEVER be used. None has proven value and some are dangerous.
|
Fever
Weight |
0 - <4 kg |
4 - <8 kg |
8 - <15 kg |
15 - <35 kg |
35 kg + |
Age |
0 - <2 mths. |
2 mths. - <1 yr. |
1 - <5 yrs. |
5 - <15 yrs. |
15 yrs. + |
Diagnosis Symptom |
|
Fever in malnourished or poor condition patient or when in doubt |
Refer |
Fever with chills35 assuming it is malaria |
Refer |
chloroquine tab 150 mg base 1/2 tab at once, then 1/2 tab after 24h and 1/2 tab after 48h |
chloroquine tab 150 mg base 1 tab at once, then 1 tab after 24h and 1/2 tab after 48h |
chloroquine tab 150 mg base 2 tab at once, then 2 tab after 24h and 1 tab after 48h |
chloroquine tab 150 mg base 4 tab at once, then 4 tab after 24h and 2 tab after 48h |
Fever with cough |
Refer |
See “Respiratory tract infections” |
Fever (unspecified) |
Refer |
paracetamol tab 100 mg 1/2 tab x 3 for 1 to 3 days |
paracetamol tab 100 mg 1 tab x 3 for 1 to 3 days |
ASA36 tab 300 mg 1 tab x 3 for 1 to 3 days |
ASA tab 300 mg 2 tab x 3 for 1 to 3 days |
35Chloroquine 150 mg base is equivalent to approximately 250 mg chloroquine phosphate or to approximately 200 mg chloroquine sulfate. See also footnote 8.
36For children under 12 paracetamol is to be preferred because of the risk of Reye’s Syndrome.
NB
Resistance to chloroquine is increasing and it is difficult to give a global recommendation for the treatment of malaria. There is an international trend to replace chloroquine with sulfadoxine + pyrimethamine. It is recommended to seek advice from the national malaria programme.
Respiratory tract infections
Weight |
0 - <4 kg |
4 - <8 kg |
8 - <15 kg |
15 - <35 kg |
35 kg + |
Age |
0 - <2 mths. |
2 mths. - <1 yr. |
1 - <5 yrs. |
5 - <15 yrs. |
15 yrs. + |
Diagnosis Symptom |
|
Severe pneumonia Annex 3 |
Give the first dose of cotrimoxazole (see pneumonia) and refer. |
Pneumonia Annex 3 |
Refer |
cotrimoxazole tab 400 mg SMX + 80 mg TMP 1/2 tab x 2 for 5 days |
cotrimoxazole tab 400 mg SMX + 80 mg TMP 1 tab x 2 for 5 days |
cotrimoxazole tab 400 mg SMX + 80 mg TMP 1 tab x 2 for 5 days |
cotrimoxazole tab 400 mg SMX + 80 mg TMP 2 tab x 2 for 5 days |
|
|
Reassess after 2 days; continue (breast) feeding, give fluids, clear the nose; return if breathing becomes faster or more difficult, or not able to drink or when the condition deteriorates. |
No pneumonia: cough or cold Annex 3 |
Refer |
paracetamol37 tab 100 mg 1/2 tab x 3 for 1 to 3 days |
paracetamol tab 100 mg 1 tab x 3 for 1 to 3 days |
ASA38 tab 300 mg 1 tab x 3 for 1 to 3 days |
ASA tab 300 mg 2 tab x 3 for 1 to 3 days |
|
|
Supportive therapy; continue (breast) feeding, give fluids, clear the nose; return if breathing becomes faster or more difficult, or not able to drink or when the condition deteriorates. |
Prolonged cough (over 30 days) |
Refer |
38For children under 12 paracetamol is to be preferred because of the risk of Reye’s Syndrome.
Ear infections
Weight |
0 - <4 kg |
4 - <8 kg |
8 - <15 kg |
15 - <35 kg |
35 kg + |
Age |
0 - <2 mths. |
2 mths. - <1 yr. |
1 - <5 yrs. |
5 - <15 yrs. |
15 yrs. + |
Diagnosis Symptom |
|
Acute ear pain and/or ear discharge for less than 2 weeks |
Refer |
cotrimoxazole tab 400 mg SMX + 80 mg TMP 1/2 tab x 2 for 5 days37 |
cotrimoxazole tab 400 mg SMX + 80 mg TMP 1 tab x 2 for 5 days37 |
cotrimoxazole tab 400 mg SMX + 80 mg TMP 1 tab x 2 for 5 days |
cotrimoxazole tab 400 mg SMX + 80 mg TMP 2 tab x 2 for 5 days |
Ear discharge for more than 2 weeks, no pain or fever |
Clean the ear once daily by syringe without needle using lukewarm clean water. Repeat until water comes out clean. Dry repeatedly with clean piece of cloth. |
37If fever is present.
Measles
Weight |
0 - <4 kg |
4 - <8 kg |
8 - <15 kg |
15 - <35 kg |
35 kg + |
Age |
0 - <2 mths. |
2 mths. - <1 yr. |
1 - <5 yrs. |
5 - <15 yrs. |
15 yrs. + |
Diagnosis Symptom |
|
|
|
Measles |
|
Treat respiratory tract disease according to symptoms. Treat conjunctivitis as “Red eyes”. Treat diarrhoea according to symptoms. Continue (breast) feeding, give retinol (vitamin A). |
|
Eyes
Red eyes (conjunctivitis) |
Apply tetracycline eye ointment 3 times a day for 7 days. If not improved after 3 days or in doubt, refer. |
Skin conditions
Wounds: extensive, deep or on face |
Refer |
Wounds: limited and superficial |
Clean with clean water and soap or diluted chlorhexidine solution39. Gently apply gentian violet solution40 once a day. |
Severe burns (on face or extensive) |
Treat as for mild burns and refer. |
Mild moderate burns |
Immerse immediately in cold water, or use a cold wet cloth. Continue until pain eases then, treat as wounds |
Severe bacterial infection (with fever) |
Refer |
Mild bacterial infection |
Clean with clean water and soap or diluted chlorhexidine solution.39 Apply gentian violet solution40 twice a day. If not improved after 10 days refer. |
Fungal infections |
Apply gentian violet solution40 once a day for 5 days. |
Infected scabies |
Bacterial infection: clean with clean water and soap or diluted chlorhexidine solution39. Apply gentian violet solution40 twice a day.
When infection is cured:
|
|
Apply diluted benzyl benzoate41 once a day for 3 days. |
Apply non diluted benzyl benzoate 25% once a day for 3 days. |
Non infected scabies |
Apply diluted benzyl benzoate41 once a day for 3 days. |
Apply non diluted benzyl benzoate25% once a day for 3 days. |
39Chlorhexidine 5% must always be diluted before use: 20 ml in 1 litre of water. Take the one litre plastic bottle supplied with the kit; put 20 ml of chlorhexidine solution into the bottle using the 10 ml syringe supplied and fill up the bottle with boiled or clean water. Chlorhexidine 1.5% + cetrimide 15% solution should be used in the same dilution.
40Gentian violet 0.5% concentration = 1 teaspoon of gentian violet powder per litre of boiled/clean water. Shake well, or use warm water to disolve all powder.
41Dilute by mixing one half litre benzyl benzoate 25% with one half litre clean water in the one litre plastic bottle supplied with the kit.
Sexually transmitted and urinary tract infections
Suspicion of sexually transmitted or urinary tract infection |
Refer |
Preventive care in pregnancy
Weight |
0 - <4 kg |
4 - <8 kg |
8 - <15 kg |
15 - <35 kg |
35 kg + |
Age |
0 - <2 mths. |
2 mths. - <1 yr. |
1 - <5 yrs. |
5 - <15 yrs. |
15 yrs. + |
Diagnosis Symptom |
|
|
|
|
|
Anaemia for treatment see under anaemia |
|
|
|
|
ferrous sulfate + folic acid 1 tab daily throughout pregnancy |
Malaria for treatment see under fever |
|
|
|
|
chloroquine42 tab 150 mg base 2 tab weekly throughout pregnancy |
42Chloroquine 150 mg base is equivalent to approximately 250 mg chloroquine phosphate or to approximately 200 mg chloroquine sulfate. See also footnote 8.
NB
Resistance to chloroquine is increasing and it is difficult to give a global recommendation for malaria prophylaxis in pregnancy. It is recommended to seek advice from the national malaria programme.
Worms43
Weight |
0 - <4 kg |
4 - <8 kg |
8 - <15 kg |
15 - <35 kg |
35 kg + |
Age |
0 - <2 mths. |
2 mths. - <1 yr. |
1 - <5 yrs. |
5 - <15 yrs. |
15 yrs. + |
Diagnosis Symptom |
|
|
|
|
|
Roundworm Pinworm |
|
|
mebendazole tab 100 mg 2 tab once |
mebendazole tab 100 mg 2 tab once |
mebendazole tab 100 mg 2 tab once |
Hookworm |
|
|
mebendazole tab 100 mg 1 tab x 2 for 3 days |
mebendazole tab 100 mg 1 tab x 2 for 3 days |
mebendazole tab 100 mg 1 tab x 2 for 3 days |
43Note: treatment of hookworm in pregnancy with mebendazole is recommended in endemic areas: mebendazole can be safely given in the second and third trimesters of pregnancy.