Malaysia. Following advice from the Malaysian Drug Control Authority, Pharmacia Corp has issued a ‘Dear Doctor’ letter advising against the off-label use of intravaginal or oral misoprostol in pregnant women for labour induction since its safety has not yet been established. In the US, the drug is approved for use with mifepristone to induce abortion in pregnancies of 49 days or less (WHO Pharmaceuticals Newsletter, No. 3, 2002).

Reference:
MADRAC News, Berita Ubat-ubatan 19:8-9, Aug 2002.