The Quality of Antimalarials - A Study in Selected African Countries - EDM Research Series No. 030
(2003; 67 pages) Voir le document au format PDF
Table des matières
Afficher le documentAuthors
Afficher le documentCountry Research Team Leaders
Afficher le documentLaboratory Support
Afficher le documentAcknowledgements
Afficher le documentAcronyms
Afficher le documentExecutive summary
Afficher le document1. Background
Ouvrir ce répertoire et afficher son contenu2. Methodology
Afficher le document3. Results
Ouvrir ce répertoire et afficher son contenu4. Discussion
Ouvrir ce répertoire et afficher son contenu5. Conclusions and recommendations
Afficher le documentReferences
Fermer ce répertoireTables
Afficher le documentTable I: Combined country results: percentage failure of samples
Afficher le documentTable II: Combined country results: percentage failure of samples at various collection points
Afficher le documentTable III: Percentage failure of samples as per origin (manufacturer)
Afficher le documentTable IV: Number of samples collected and analysed
Afficher le documentTable IVa: Country results from various collection points - Participating country: Gabon
Afficher le documentTable IVb: Country results from various collection points - Participating country: Ghana
Afficher le documentTable IVc: Country results from various collection points - Participating country: Kenya
Afficher le documentTable IVd: Country results from various collection points - Participating country: Mali
Afficher le documentTable IVe: Country results from various collection points - Participating country: Mozambique
Afficher le documentTable IVf: Country results from various collection points - Participating country: Zimbabwe
Afficher le documentTable IVg: Country results from various collection points - Participating country: Sudan
Afficher le documentTable Va: Country results according to origin of manufacturer - Participating country: Gabon
Afficher le documentTable Vb: Country results according to origin of manufacturer - Participating country: Ghana
Afficher le documentTable Vc: Country results according to origin of manufacturer - Participating country: Kenya
Afficher le documentTable Vd: Country results according to origin of manufacturer - Participating country: Mali
Afficher le documentTable Ve: Country results according to origin of manufacturer - Participating country: Mozambique
Afficher le documentTable Vf: Country results according to origin of manufacturer - Participating country: Zimbabwe
Ouvrir ce répertoire et afficher son contenuAnnexes
Afficher le documentOther documents in the EDM Research Series
Afficher le documentEDM Research Series No. 30
 

Table I: Combined country results: percentage failure of samples

Country

Chloroquine syrup

Chloroquine tablets

Sulphadoxine/pyrimethamine tablets*

 

Content

Content

Dissolution

Content

Dissolution

Gabon

0
(0/8)

29.0
(5/17)

5.8
(1/7)

0
(0/10)

-

Ghana

5.0
(1/20)

66.7
(12/18)

20.0
(3/15)

37.5
(3/8)

75.0
(3/4)

Mali

66.7
(4/6)

47.3
(9/19)

5.2
(1/19)

0
(0/7)

100
(7/7)

Kenya

25.0
(2/8)

42.8
(3/7)

28.6
(2/7)

0
(0/12)

91.7
(11/12)

Mozambique

25.0
(3/12)

20.0
(3/15)

6.7
(1/15)

5.5
(1/18)

100
(18/18)

Sudan

26.6
(4/15

5.2
(1/19)

12.5
(2/16)

0
(0/20)

80.0
(12/15)

Zimbabwe

13.3
(2/15)

57.1
(8/14)

7.1
(1/14)

10.0
(1/10)

100
(10/10)

Average failure (%)

23.0

38.3

12.2

7.6

91.1 (n=6)

Range (%)

0 - 66.7

20 - 66.7

5.2 - 28.6

0 - 37.5

75 - 100 (n=6)

 

*Indicated as % failure due to the content and dissolution rate of the pyrimethamine component


Fig. 1. Percentage failure - chloroquine syrup


Fig. 2. Percentage failure - chloroquine tablets (content)


Fig. 2a. Content (%) - chloroquine tablets


Fig. 3. Percentage failure - chloroquine tablets (dissolution)


Fig. 4. Percentage failure - sulphadoxine/pyrimethaminetablets (pyrimethamine content)


Fig. 5. Percentage failure - sulphadoxine/pyrimethaminetablets (pyrimethamine dissolution)


Fig. 5a. Sulphadoxine/pyrimethamine tablets - pyrimethaminedissolution (%)

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