WHO Pharmaceuticals Newsletter 1999, No. 03&04
(1999; 16 pages)

Table des matières

	Regulatory actions
		Alatrofloxacin: revised labelling: incompatibility with certain diluents: Pfizer, USA
		Beclometasone: recommended total daily dose in CFC-free inhalers: UK
		Cholestin reinstated as a dietary product: federal judge overrules FDA decision: USA
		Fluticasone: revised package insert: systemic eosinophilia: Glaxo Wellcome
		Fosphenytoin sodium injection (Cerebyx): overdoses due to medication errors: label changes: Parke-Davis
		Heparin-induced suppression of aldosterone secretion: product information revised: UK
		Laxatives containing dantron and phenolphthalein: unacceptable ingredients in OTC drug products: USA
		Nicotine chewing gum: available for general sale: UK
		Nonprescription drugs: simplified labelling: USA
		Rituximab (Mabthera): recommendations for safe use: UK
		Troglitazone: application for re-introduction rejected: UK
	Drug surveillance
		ACE inhibitors: survey of renal monitoring: UK
		Acenocoumarol: alopecia: Spain
		Anti-thyroid drugs: agranulocytosis: UK
		Cannabis: two clinical trials to start soon: UK
		Clozapine: gastrointestinal obstruction: UK
		Donepezil: review of adverse reactions: seizure and heart block: UK
		Drugs and children: ADR reporting: new rules for paediatric trials of medicines: unlicensed drug use in neonates: UK
		Ergotamine: interaction with HIV protease inhibitors: France, Switzerland
		Fexofenadine: cardiac reaction: Netherlands
		Inhaled corticosteroids: peri-oral dermatitis: Israel
		Mirtazepine: intrahepatic cholestasis: Finland
		Nicorandil: mouth ulcers: France
		Orlistat: caution against nonprescription use: UK
		Sildenafil: interaction with HIV protease inhibitors: UK
		Sucralfate: bezoar formation: UK
		Topiramate: transient hemiparesis: UK
	New developments
		Denileukin diftitox: novel treatment for rare form of cancer approved: USA
		Desirudin: approved for use in orthopaedic surgery: UK
		Etonorgestrel: single implant contraceptive: UK
		Levonorgestrel: progestogen-only emergency contraception available: UK
		Maggots: use in infected and necrotic wounds: UK
		Temozolomide: a new treatment for brain cancer: UK
		Vaccine for Lyme disease: approved: USA
		New indications
		New formulations
		Newly approved products
	Medical devices
		Blood test for Lyme disease: approved: USA
		Drug delivery systems: new devices under development: UK, USA
		Wound dressings: pain-free removal: UK
	Medication errors
		Antimalarials: potential for prescribing errors: Netherlands
		Celebrex: potential for errors: call to rename: USA
		Equivalence code: potential to increase errors: USA
		Syringe tip caps: potential hazard to infants: USA
	Veterinary medicine
		Antibiotics: four products banned from poultry and pig feeds: EU
		Decoquinate: approved for the prevention of coccidiosis in calves: USA
		Florfenicol: approved for the treatment of foot rot: USA
		Narasin and nicarbazin with bacitracin methylene disalicylate: approved in broiler chicken feeds for prevention of coccidiosis: USA

WHO Pharmaceuticals Newsletter 1999, No. 03&04

Essential Drugs and Medicines Policy

WHO.INT

World Health Organization