WHO Model Prescribing Information: Drugs Used in Skin Diseases
(1997; 132 pages) [French] [Spanish] Voir le document au format PDF
Table des matières
Afficher le documentPreface
Afficher le documentIntroduction
Ouvrir ce répertoire et afficher son contenuParasitic infections
Ouvrir ce répertoire et afficher son contenuInsect and arachnid bites and stings
Ouvrir ce répertoire et afficher son contenuSuperficial fungal infections
Ouvrir ce répertoire et afficher son contenuSubcutaneous fungal infections
Ouvrir ce répertoire et afficher son contenuBacterial infections
Ouvrir ce répertoire et afficher son contenuViral infections
Ouvrir ce répertoire et afficher son contenuEczematous diseases
Ouvrir ce répertoire et afficher son contenuScaling diseases
Ouvrir ce répertoire et afficher son contenuPapulosquamous diseases
Afficher le documentCutaneous reactions to drugs
Ouvrir ce répertoire et afficher son contenuPigmentary disorders
Fermer ce répertoirePremalignant lesions and malignant tumours
Afficher le documentActinic keratosis
Afficher le documentBasal cell and squamous cell carcinomas
Afficher le documentMalignant melanoma
Ouvrir ce répertoire et afficher son contenuPhotodermatoses
Ouvrir ce répertoire et afficher son contenuBullous dermatoses
Afficher le documentAlopecia areata
Afficher le documentUrticaria
Ouvrir ce répertoire et afficher son contenuConditions common in children
Afficher le documentAcne vulgaris
Afficher le documentPruritus
Afficher le documentTropical ulcers
Ouvrir ce répertoire et afficher son contenuAntimicrobial drugs
Ouvrir ce répertoire et afficher son contenuAntifugal drugs
Ouvrir ce répertoire et afficher son contenuAntiseptic agents
Ouvrir ce répertoire et afficher son contenuKeratoplastic and keratolytic agents
Ouvrir ce répertoire et afficher son contenuScabicides and pediculicides
Ouvrir ce répertoire et afficher son contenuAnti-inflammatory and antipruritic drugs1
Ouvrir ce répertoire et afficher son contenuAntiallergics and drugs used in anaphylaxis
Ouvrir ce répertoire et afficher son contenuUltraviolet radiation-blocking agents (sunscreens)
Ouvrir ce répertoire et afficher son contenuMiscellaneous drugs
Ouvrir ce répertoire et afficher son contenuAnnex
Afficher le documentSelected WHO Publications of Related Interest
Afficher le documentBack cover
 

Premalignant lesions and malignant tumours

Exposure of skin to sunlight is beneficial in moderation since ultraviolet radiation is vital to the synthesis of vitamin D and hence to satisfactory skeletal development. Excessive exposure, however, is hazardous, particularly in light-skinned persons who tan poorly, and in patients who are photosensitive. There is also evidence that ultraviolet light decreases the immunological responses of the skin.

Photodamage is first evident as acute sunburn and, in the longer term, as premature ageing of the skin. Excessive exposure to sunlight also predisposes to the development of malignant and premalignant skin lesions, including actinic keratosis, squamous cell and basal cell carcinoma, and malignant melanoma.

The incidence of malignant and premalignant conditions is particularly high among light-skinned persons living in hot sunny climates and in dark-skinned persons with vitiligo or albinism. Many cases could be prevented by persuading parents and individuals directly at risk of the importance of avoiding sunburn and reducing exposure to solar radiation. Photoprotection in children is a priority all over the world, and every effort should be made to institute educational programmes on protection against the sun at a very early age. The use of protective clothing (e.g. tightly woven fabrics, wide-brimmed hats, long sleeves and long trousers) is highly effective. When this is not practicable or acceptable, it is important to encourage regular use of sunscreen products with a SPF rating of at least 15. People should understand that the atmosphere has a filtering effect on ultraviolet light and, therefore, they should avoid exposure at midday when the sun is most vertical and the light passes through less of the atmosphere.

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Dernière mise à jour: le 24 avril 2012