Building Local Coalitions for Containing Drug Resistance: A Guide
(2011; 207 pages)

Management Sciences for Health. 2011. Building Local Coalitions for Containing Drug Resistance: A Guide. Submitted to the U.S. Agency for International Development by the Strengthening Pharmaceutical Systems (SPS) Program. Arlington, VA: Management Sciences for Health.


As part of its Infectious Disease Initiative, the US Agency for International Development (USAID) supports efforts to raise awareness of drug resistance and to limit its emergence and spread by decreasing the use of antimicrobial medicines when they are not required, improving their use when they are required, and improving the quality and supply of medicines. A key first step was supporting the development of the World Health Organization Global Strategy for the Containment of Antimicrobial Resistance. The Global Strategy provides a comprehensive set of evidence- and consensus-based recommendations for antimicrobial resistance (AMR) containment through interventions that target various stakeholders, including health providers, patients, governments, and health systems. This guide builds on the Global Strategy by offering a practical approach to operationalize the strategy at the local level and by making tools and approaches readily available to support advocacy and coalition building around the issue and act accordingly.

The first version of this guide, Workbook for Building Local Support for Containing Drug Resistance, was developed in 2004 by the Academy for Educational Development (AED) through the Behavior Change Innovation: State of the Art Activity (CHANGE) Project, the Harvard Drug Policy Research Group through the Applied Research on Child Health Project, Management Sciences for Health (MSH) through the Rational Pharmaceutical Management (RPM) Plus Program, and the Alliance for the Prudent Use of Antibiotics funded through RPM Plus.

The guide was updated in 2008 by the RPM Plus Program. It was based largely on the initial version and modified on the basis of feedback from users. This newly revised version has been published by the Strengthening Pharmaceutical Systems (SPS) Program, which is a follow-on to RPM Plus. Updates reflect additional work since the 2008 publication, particularly related to regional AMR advocacy and coalition building. This guide also includes examples of activities, tools, and templates to enhance its practical applicability in the field.

This guide aims to help AMR stakeholders organize a collaborative effort to locally address drug resistance. The priority interventions outlined in the WHO Global Strategy are coupled with advocacy efforts to achieve the critical mass of activity needed for a coordinated, multidisciplinary, coalition-based approach to containing drug resistance.

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