The problems of fake drug proliferation in Nigeria have affected the credibility of the Healthcare system and can exert very harmful effects on the consumer resulting to illness; disability and even death and anyone can be a victim. Some of the incidences have resulted in death even among children because most times the consumers do not know the quality of what they are buying or taking. This makes it imperative that there is need to intensify effort in fake drug eradication. National Agency for Food and Drug Administration and Control (NAFDAC) is the government agency in Nigeria that is fully empowered to regulate and control the importation, exportation, manufacture, advertisement, distribution, sale and use of drugs in order to ensure that safe and quality drugs are available to the public. As NAFDAC tasks herself dutifully in fighting fake drugs, more challenges comes up from unscrupulous drug dealer who sometimes have the backings of lawmakers and politicians making the stipulated drug laws and standard unattainable.