Guide to Good Prescribing - A Practical Manual
(1994; 115 pages) [French] [Spanish] Ver el documento en el formato PDF
Índice de contenido
Ver el documentoAcknowledgments
Ver el documentoWhy you need this book
Abrir esta carpeta y ver su contenidoPart 1: Overview
Abrir esta carpeta y ver su contenidoPart 2: Selecting your P(ersonal) drugs
Abrir esta carpeta y ver su contenidoPart 3: Treating your patients
Abrir esta carpeta y ver su contenidoPart 4: Keeping up-to-date
Cerrar esta carpetaAnnexes
Cerrar esta carpetaAnnex 1: Essentials of pharmacology in daily practice
Ver el documentoIntroduction
Cerrar esta carpetaPharmacodynamics
Ver el documentoThe Cp/response curve
Abrir esta carpeta y ver su contenidoPharmacokinetics
Abrir esta carpeta y ver su contenidoDrug treatment
Abrir esta carpeta y ver su contenidoSpecial features of the curve
Ver el documentoAnnex 2: Essential references
Abrir esta carpeta y ver su contenidoAnnex 3: How to explain the use of some dosage forms
Abrir esta carpeta y ver su contenidoAnnex 4. The use of injections
Ver el documentoBack Cover
 

Pharmacodynamics

The effects of a drug are usually presented in a dose-response curve. The effect of the drug is plotted on the Y-axis and the dose on the X-axis (Figure 10). The dose is usually plotted on a logarithmic scale. The higher the dose the stronger the effect, until the effect levels off to a maximum. The effect is usually expressed as a percentage of the maximum. The maximum effect of one drug may be more than that of another. Desired and side effects can both be plotted in dose-response curves.


Figure 10: Dose-response curve

The dose is usually expressed per kilogram body weight or per m2 body surface area. However, the most accurate way is to use the plasma concentration, because it excludes differences in absorption and elimination of the drug. In the following text the plasma concentration-response curve (Cp/response curve) is used.

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Última actualización: le 3 mayo 2013