Remarks: |
Comparison made both for dark storage at 30C and room temperature in light |
| |
Values represent mean level of active ingredient of two batch values |
| |
Batch value represents mean of two separate ampoule values. |
Special production (E3 and M4)* |
|
|
E2 and M2 (same brand)** |
| |
Dark, 30C |
Light, 21-25C |
|
|
Dark, 30C |
Light, 21-25C |
Time |
ErDa |
MeDa |
ErLi |
MeLi |
|
Time |
ErDa |
MeDa |
ErLi |
MeLi |
0 |
101 |
106 |
101 |
106 |
|
0 |
100 |
100 |
100 |
100 |
0.5 |
103 |
106 |
60 |
70 |
|
0.5 |
97 |
94 |
96 |
91 |
1 |
100 |
105 |
44 |
41 |
|
1 |
94 |
90 |
88 |
76 |
2 |
98 |
104 |
6 |
6 |
|
2 |
84 |
87 |
79 |
48 |
3 |
99 |
99 |
0 |
0 |
|
3 |
77 |
83 |
36 |
24 |
6 |
94 |
98 |
0 |
0 |
|
6 |
58 |
71 |
9 |
8 |
12 |
84 |
90 |
0 |
0 |
|
12 |
44 |
58 |
4 |
4 |
m |
|
|
|
|
|
m |
|
|
|
|
* Active ingredient, as % of stated amount |
|
** As percentage of initial amount of active ingredient |
Special production
E2 and M2 (same brand)
LEGEND
Er = ergometrine; Me = methylergometrine; Da = dark, 30C; Li = light, 21-25C
Other documents in the DAP Research Series
N°. 1 Injection practices research
N°. 2 How to investigate drug use in communities (available also in French)
N°. 3 Operational research on the rational use of drugs
N°. 4 Development of indicators for monitoring national drug policies
N°. 5 People's perception and use of drugs in Zimbabwe
N°. 6 Operational research in the Action Programme on Essential Drugs: Report of an informal consultation
N°. 7 How to investigate drug use in health facilities: Selected drug use indicators
DAP Research Series No. 8
In 1981 WHO'S Action Programme on Essential Drugs was established to provide operational support to countries in the development of national drug policies based on essential drugs and to work towards the rational use of drugs.
The Programme seeks to ensure that all people, wherever they may be, are able to obtain the drugs they need at a price that they and their country can afford; that these drugs are safe, effective and of good quality; and that they are prescribed arid used rationally.
Research analysing the impediments to developing and managing sound national drug policies and programmes is an important element of country support activities. The Programme undertakes and promotes operational research aimed at filling some of the many gaps in existing knowledge about the best means of selecting, procuring and distributing drugs, and their use by preservers and consumers.
This document is part of a series reporting on Action Programme research activities and guidelines.
Research that leads to breakthroughs in pharmaceutical technology or in highly sophisticated and expensive techniques of biomedical practice may superficially appear to be more "glamorous". But the operational research that WHO'S Action Programme on Essential Drugs undertakes has a direct bearing on the ways in which vital medicines can be made available and accessible to the greatest number of people.
Action Programme on Essential Drugs, World Health Organization, 1211 Geneva 27, Switzerland
Cargando...
